Factors to be considered when choosing induction therapy
| Patient related . | Disease related . | Treatment related . |
|---|---|---|
| Age/Fitness | Bone marrow disease burden | Access to standard-of-care therapies |
| Caregiver support | Extramedullary disease | Costs and copays |
| Comorbidities | Molecular cytogenetics/genomics | Route of administration |
| Compliance | CRAB symptoms | Clinical trial availability |
| Lifestyle preferences | R-ISS/ISS | Toxicity |
| Performance status/Frailty |
| Patient related . | Disease related . | Treatment related . |
|---|---|---|
| Age/Fitness | Bone marrow disease burden | Access to standard-of-care therapies |
| Caregiver support | Extramedullary disease | Costs and copays |
| Comorbidities | Molecular cytogenetics/genomics | Route of administration |
| Compliance | CRAB symptoms | Clinical trial availability |
| Lifestyle preferences | R-ISS/ISS | Toxicity |
| Performance status/Frailty |
ISS, International Staging System; R-ISS, Revised International Staging System.