Examples of pregnancy-specific causes and general causes for thrombocytopenia during pregnancy
| Pregnancy specific |
| Gestational thrombocytopenia |
| Preeclampsia with severe features |
| Eclampsia |
| HELLP |
| Acute fatty liver of pregnancy |
| General* |
| Immune thrombocytopenia |
| Hereditary thrombocytopenia |
| Type 2B von Willebrand disease |
| Drug-induced thrombocytopenia |
| Infections |
| Cirrhosis |
| Splenomegaly |
| Bone marrow disorders (eg, aplastic anemia, myelodysplastic syndrome, leukemia/lymphoma) |
| Paroxysmal nocturnal hemoglobinuria |
| Complement-mediated thrombotic microangiopathy |
| TTP |
| Autoimmune disorders (eg, lupus, antiphospholipid syndrome) |
| Disseminated intravascular coagulation |
| Pregnancy specific |
| Gestational thrombocytopenia |
| Preeclampsia with severe features |
| Eclampsia |
| HELLP |
| Acute fatty liver of pregnancy |
| General* |
| Immune thrombocytopenia |
| Hereditary thrombocytopenia |
| Type 2B von Willebrand disease |
| Drug-induced thrombocytopenia |
| Infections |
| Cirrhosis |
| Splenomegaly |
| Bone marrow disorders (eg, aplastic anemia, myelodysplastic syndrome, leukemia/lymphoma) |
| Paroxysmal nocturnal hemoglobinuria |
| Complement-mediated thrombotic microangiopathy |
| TTP |
| Autoimmune disorders (eg, lupus, antiphospholipid syndrome) |
| Disseminated intravascular coagulation |
Table based on Gernsheimer et al.2
List of examples diagnoses to consider, not inclusive of all possible diagnoses.