Table 2.

Comparison of romiplostim-treated patients and retrospective data

NDays of plt transfusions or G4 thrombocytopenia median (range)Days of plt transfusions or G4 thrombocytopenia mean (IQR)Plt transfusions per patient median (range)Plt transfusions per patient mean (IQR)
Romiplostim MM
Melphalan 
40 6 (0-17) 6.2 (4-8) 2 (0-7) 2.2 (1-3) 
 Lymphoma
BEAM; TBC 
19 11 (4-17) 10.9 (8.5-13.5) 5 (2-10) 5.1 (3-6.5) 
Retrospective data MM
Melphalan 
485 5 (0-53) 6.8 (3-8) 2 (0-19) 2.7 (1-3) 
 Lymphoma
BEAM/CBV
TBC 
296
73 
8 (2-68)
10 (5-38) 
9.5 (6-10)
12 (8-13) 
4 (0-44)
5 (2-32) 
5 (3-6)
6.3 (4-7) 
NDays of plt transfusions or G4 thrombocytopenia median (range)Days of plt transfusions or G4 thrombocytopenia mean (IQR)Plt transfusions per patient median (range)Plt transfusions per patient mean (IQR)
Romiplostim MM
Melphalan 
40 6 (0-17) 6.2 (4-8) 2 (0-7) 2.2 (1-3) 
 Lymphoma
BEAM; TBC 
19 11 (4-17) 10.9 (8.5-13.5) 5 (2-10) 5.1 (3-6.5) 
Retrospective data MM
Melphalan 
485 5 (0-53) 6.8 (3-8) 2 (0-19) 2.7 (1-3) 
 Lymphoma
BEAM/CBV
TBC 
296
73 
8 (2-68)
10 (5-38) 
9.5 (6-10)
12 (8-13) 
4 (0-44)
5 (2-32) 
5 (3-6)
6.3 (4-7) 

BEAM, carmustine, etoposide, cytarabine, melphalan; CBV, cyclophosphamide, carmustine, etoposide; G4, grade 4; plts, platelet(s); TBC, thiotepa, busulfan, cyclophosphamide.

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