Ten DEGs during stimulated VWF release with the greatest fold change
| Gene . | Protein . | Function . | Log2 fold change . | Adjusted P value . |
|---|---|---|---|---|
| LCP2 | Lymphocyte cytosolic protein 2 | Promotes T-cell development and activation, as well as mast cell and platelet function | 6.46 | 1.86E-02 |
| MEST | Mesoderm specific transcript | Involved in the metabolism pathways that affect growth and maintenance of mesodermal cells | 6.22 | 9.48E-02 |
| SCN3A | Sodium voltage-gated channel alpha subunit 3 | Mediates the voltage-dependent sodium ion permeability of excitable membranes | −6.18 | 2.26E-02 |
| PCDH10 | PCDH10 | Potential calcium-dependent cell-adhesion protein | 6.03 | 2.46E-03 |
| CDH11 | Cadherin 11 | Calcium-dependent cell adhesion protein | 5.95 | 9.72E-02 |
| RET | RET | Receptor tyrosine-protein kinase involved in cell proliferation, neuronal navigation, cell migration, and cell differentiation | −5.77 | 6.14E-02 |
| SERPINB2 | Serpin family B member 2 | Inhibits urokinase-type plasminogen activator | 5.53 | 3.37E-02 |
| EMILIN1 | Elastin microfibril interfacer 1 | Extracellular matrix structural constituent; may be involved in the regulation of vessel assembly | −5.36 | 8.51E-02 |
| RBP1 | Retinol binding protein 1 | Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage, and retinoid homeostasis | −5.33 | 3.37E-02 |
| BRSK2 | BR serine/threonine kinase 2 | Serine/threonine-protein kinase that plays a key role in polarization of neurons and axonogenesis, cell cycle progress and insulin secretion | −5.32 | 7.01E-02 |
| Gene . | Protein . | Function . | Log2 fold change . | Adjusted P value . |
|---|---|---|---|---|
| LCP2 | Lymphocyte cytosolic protein 2 | Promotes T-cell development and activation, as well as mast cell and platelet function | 6.46 | 1.86E-02 |
| MEST | Mesoderm specific transcript | Involved in the metabolism pathways that affect growth and maintenance of mesodermal cells | 6.22 | 9.48E-02 |
| SCN3A | Sodium voltage-gated channel alpha subunit 3 | Mediates the voltage-dependent sodium ion permeability of excitable membranes | −6.18 | 2.26E-02 |
| PCDH10 | PCDH10 | Potential calcium-dependent cell-adhesion protein | 6.03 | 2.46E-03 |
| CDH11 | Cadherin 11 | Calcium-dependent cell adhesion protein | 5.95 | 9.72E-02 |
| RET | RET | Receptor tyrosine-protein kinase involved in cell proliferation, neuronal navigation, cell migration, and cell differentiation | −5.77 | 6.14E-02 |
| SERPINB2 | Serpin family B member 2 | Inhibits urokinase-type plasminogen activator | 5.53 | 3.37E-02 |
| EMILIN1 | Elastin microfibril interfacer 1 | Extracellular matrix structural constituent; may be involved in the regulation of vessel assembly | −5.36 | 8.51E-02 |
| RBP1 | Retinol binding protein 1 | Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage, and retinoid homeostasis | −5.33 | 3.37E-02 |
| BRSK2 | BR serine/threonine kinase 2 | Serine/threonine-protein kinase that plays a key role in polarization of neurons and axonogenesis, cell cycle progress and insulin secretion | −5.32 | 7.01E-02 |