Table 4.

Univariate analysis of impact of sirolimus on CMV reactivation among MMF and PTCy recipients before day 100

MMF
CMV reactivation before d 100Number of patientsNumber of patients with reactivationSirolimusHR (95% CI)P
>0 IU/mL 351 261 No  
 63 39 Yes 0.65 (0.47-0.89) .007 
≥250 IU/mL 351 146 No  
 63 15 Yes 0.51 (0.30-0.87) .013 
≥1000 IU/mL 351 61 No  
 63 Yes 0.25 (0.08-0.80) .019 
MMF
CMV reactivation before d 100Number of patientsNumber of patients with reactivationSirolimusHR (95% CI)P
>0 IU/mL 351 261 No  
 63 39 Yes 0.65 (0.47-0.89) .007 
≥250 IU/mL 351 146 No  
 63 15 Yes 0.51 (0.30-0.87) .013 
≥1000 IU/mL 351 61 No  
 63 Yes 0.25 (0.08-0.80) .019 
PTCy
CMV reactivation before d 100Number of patientsNumber of patients with reactivationSirolimusHR (95% CI)P
>0 IU/mL 36 25 No  
 Yes 1.22 (0.51-2.91) .651 
≥250 IU/mL 36 17 No  
 Yes 1.31 (0.53-3.22) .556 
PTCy
CMV reactivation before d 100Number of patientsNumber of patients with reactivationSirolimusHR (95% CI)P
>0 IU/mL 36 25 No  
 Yes 1.22 (0.51-2.91) .651 
≥250 IU/mL 36 17 No  
 Yes 1.31 (0.53-3.22) .556 
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