Multivariable analyses of risk factors for OS and EFS
| Risk factor . | Group . | At risk (N) . | Events (N) . | HR (95% CI) . | P value . | LRT∗ . |
|---|---|---|---|---|---|---|
| OS | ||||||
| IEI subgroup | CID | 127 | 39 | 0.052 | ||
| PAD | 30 | 15 | 1.49 (0.78-2.86) | .2 | ||
| PD | 102 | 21 | 0.62 (0.36-1.07) | .09 | ||
| IEI complications | No complication | 88 | 18 | 0.062 | ||
| 1 complication | 91 | 24 | 1.02 (0.54-1.94) | .9 | ||
| ≥2 complications | 80 | 33 | 1.84 (0.98-3.48) | .06 | ||
| Age at HSCT | (decades) | 259 | 75 | 1.13 (0.87-1.46) | .4 | 0.378 |
| HCT-CI score | 0 | 68 | 17 | 0.103 | ||
| 1-2 | 105 | 23 | 0.87 (0.45-1.67) | .7 | ||
| >2 | 86 | 35 | 1.54 (0.82-2.9) | .18 | ||
| Conditioning intensity | MA | 69 | 26 | 0.32 | ||
| RTC | 169 | 44 | 0.69 (0.42-1.13) | .14 | ||
| NMA | 21 | 5 | 0.66 (0.25-1.76) | .4 | ||
| EFS | ||||||
| IEI subgroup | CID | 122 | 50 | 0.142 | ||
| PAD | 30 | 17 | 1.38 (0.76-2.48) | .3 | ||
| PD | 101 | 33 | 0.73 (0.47-1.16) | .18 | ||
| IEI complications | No complication | 86 | 27 | 0.05 | ||
| 1 complication | 88 | 32 | 1.06 (0.62-1.8) | .8 | ||
| ≥2 complications | 79 | 41 | 1.78 (1.04-3.04) | .035 | ||
| Age at HSCT | (decades) | 253 | 100 | 1.15 (0.92-1.44) | .2 | 0.249 |
| HCT-CI score | 0 | 64 | 23 | 0.774 | ||
| 1-2 | 104 | 38 | 0.92 (0.53-1.59) | 0.8 | ||
| > 2 | 85 | 39 | 1.09 (0.62-1.91) | 0.8 | ||
| Conditioning intensity | MA | 68 | 27 | 0.958 | ||
| RTC | 164 | 65 | 1.05 (0.66-1.66) | 0.8 | ||
| NMA | 21 | 8 | 0.96 (0.43-2.15) | 0.9 | ||
| Risk factor . | Group . | At risk (N) . | Events (N) . | HR (95% CI) . | P value . | LRT∗ . |
|---|---|---|---|---|---|---|
| OS | ||||||
| IEI subgroup | CID | 127 | 39 | 0.052 | ||
| PAD | 30 | 15 | 1.49 (0.78-2.86) | .2 | ||
| PD | 102 | 21 | 0.62 (0.36-1.07) | .09 | ||
| IEI complications | No complication | 88 | 18 | 0.062 | ||
| 1 complication | 91 | 24 | 1.02 (0.54-1.94) | .9 | ||
| ≥2 complications | 80 | 33 | 1.84 (0.98-3.48) | .06 | ||
| Age at HSCT | (decades) | 259 | 75 | 1.13 (0.87-1.46) | .4 | 0.378 |
| HCT-CI score | 0 | 68 | 17 | 0.103 | ||
| 1-2 | 105 | 23 | 0.87 (0.45-1.67) | .7 | ||
| >2 | 86 | 35 | 1.54 (0.82-2.9) | .18 | ||
| Conditioning intensity | MA | 69 | 26 | 0.32 | ||
| RTC | 169 | 44 | 0.69 (0.42-1.13) | .14 | ||
| NMA | 21 | 5 | 0.66 (0.25-1.76) | .4 | ||
| EFS | ||||||
| IEI subgroup | CID | 122 | 50 | 0.142 | ||
| PAD | 30 | 17 | 1.38 (0.76-2.48) | .3 | ||
| PD | 101 | 33 | 0.73 (0.47-1.16) | .18 | ||
| IEI complications | No complication | 86 | 27 | 0.05 | ||
| 1 complication | 88 | 32 | 1.06 (0.62-1.8) | .8 | ||
| ≥2 complications | 79 | 41 | 1.78 (1.04-3.04) | .035 | ||
| Age at HSCT | (decades) | 253 | 100 | 1.15 (0.92-1.44) | .2 | 0.249 |
| HCT-CI score | 0 | 64 | 23 | 0.774 | ||
| 1-2 | 104 | 38 | 0.92 (0.53-1.59) | 0.8 | ||
| > 2 | 85 | 39 | 1.09 (0.62-1.91) | 0.8 | ||
| Conditioning intensity | MA | 68 | 27 | 0.958 | ||
| RTC | 164 | 65 | 1.05 (0.66-1.66) | 0.8 | ||
| NMA | 21 | 8 | 0.96 (0.43-2.15) | 0.9 | ||
LRT, likelihood ratio test.
P value for: does this risk factor add information when the other risk factors are already in the model? (<.05 = yes).