Etiology of GNB PE-BSI and AMR, according to levofloxacin prophylaxis use (group A, ASCT LEVO-group; group B, ASCT NO-LEVO-group; group C, allo-HSCT LEVO-group; group D, allo--HSCT NO-LEVO-group)
| Blood cultures’ isolates characteristics . | Total bacterial isolates from blood cultures . | |||||
|---|---|---|---|---|---|---|
| Group A . | Group B . | P value . | Group C . | Group D . | P value . | |
| GNB | 0 | 13 | - | 10 | 58 | |
| GNB resistant to PTZ | 0 (0%) | 2 (15%) | - | 7 (70%) | 17 (29%) | .027 |
| GNB resistant to FQs | 0 (0%) | 2 (15%) | - | 9 (90%) | 30 (52%) | .036 |
| CR-GNB | 0 (0%) | 0 (0%) | - | 5 (50%) | 3 (5%) | .001 |
| E coli | 0 (0%) | 10 (77%) | - | 4 (40%) | 26 (45%) | |
| E coli ESBL-producing | 0 (0%) | 0 (0%) | 2 (50%) | 7 (27%) | ||
| E coli resistant to FQs | 0 (0%) | 1 (10%) | 4 (100%) | 15 (58%) | ||
| E coli resistant to PTZ | 0 (0%) | 2 (20%) | 2 (50%) | 6 (23%) | ||
| CR-E coli | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | ||
| K pneumoniae | 0 (0%) | 1 (8%) | - | 4 (40%) | 13 (22%) | .254 |
| K pneumoniae ESBL-producing | 0 (0%) | 1 (100%) | 0 (0%) | 7 (54%) | ||
| K pneumoniae resistant to FQs | 0 (0%) | 1 (100%) | 4 (100%) | 6 (46%) | ||
| K pneumoniae resistant to PTZ | 0 (0%) | 0 (0%) | 4 (100%) | 6 (46%) | ||
| CR-K pneumoniae | 0 (0%) | 0 (0%) | 4 (100%) | 0 (0%) | ||
| Other Enterobacteriaceae∗ | 0 (0%) | 0 (0%) | - | 0 (0%) | 3 (5%) | - |
| P aeruginosa | 0 (0%) | 2 (15%) | - | 2 (20%) | 8 (14%) | .634 |
| P aeruginosa resistant to FQs | 0 (0%) | 0 (0%) | 1 (50%) | 4 (50%) | ||
| P aeruginosa resistant to PTZ | 0 (0%) | 0 (0%) | 1 (50%) | 3 (37%) | ||
| CR-P aeruginosa | 0 (0%) | 0 (0%) | 1 (50%) | 3 (37%) | ||
| Other GNB† | 0 (0%) | 0 (0%) | - | 0 (0%) | 8 (14%) | - |
| Blood cultures’ isolates characteristics . | Total bacterial isolates from blood cultures . | |||||
|---|---|---|---|---|---|---|
| Group A . | Group B . | P value . | Group C . | Group D . | P value . | |
| GNB | 0 | 13 | - | 10 | 58 | |
| GNB resistant to PTZ | 0 (0%) | 2 (15%) | - | 7 (70%) | 17 (29%) | .027 |
| GNB resistant to FQs | 0 (0%) | 2 (15%) | - | 9 (90%) | 30 (52%) | .036 |
| CR-GNB | 0 (0%) | 0 (0%) | - | 5 (50%) | 3 (5%) | .001 |
| E coli | 0 (0%) | 10 (77%) | - | 4 (40%) | 26 (45%) | |
| E coli ESBL-producing | 0 (0%) | 0 (0%) | 2 (50%) | 7 (27%) | ||
| E coli resistant to FQs | 0 (0%) | 1 (10%) | 4 (100%) | 15 (58%) | ||
| E coli resistant to PTZ | 0 (0%) | 2 (20%) | 2 (50%) | 6 (23%) | ||
| CR-E coli | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | ||
| K pneumoniae | 0 (0%) | 1 (8%) | - | 4 (40%) | 13 (22%) | .254 |
| K pneumoniae ESBL-producing | 0 (0%) | 1 (100%) | 0 (0%) | 7 (54%) | ||
| K pneumoniae resistant to FQs | 0 (0%) | 1 (100%) | 4 (100%) | 6 (46%) | ||
| K pneumoniae resistant to PTZ | 0 (0%) | 0 (0%) | 4 (100%) | 6 (46%) | ||
| CR-K pneumoniae | 0 (0%) | 0 (0%) | 4 (100%) | 0 (0%) | ||
| Other Enterobacteriaceae∗ | 0 (0%) | 0 (0%) | - | 0 (0%) | 3 (5%) | - |
| P aeruginosa | 0 (0%) | 2 (15%) | - | 2 (20%) | 8 (14%) | .634 |
| P aeruginosa resistant to FQs | 0 (0%) | 0 (0%) | 1 (50%) | 4 (50%) | ||
| P aeruginosa resistant to PTZ | 0 (0%) | 0 (0%) | 1 (50%) | 3 (37%) | ||
| CR-P aeruginosa | 0 (0%) | 0 (0%) | 1 (50%) | 3 (37%) | ||
| Other GNB† | 0 (0%) | 0 (0%) | - | 0 (0%) | 8 (14%) | - |
Bold values represent P values that reach statistical significance (P < 0.05). PTZ, piperacillin/tazobactam.
1 Klebsiella oxytoca, 1 Enterobacter cloacae, 1 Proteus mirabilis.
Two Ochrobactrum anthropi, 1 Stenotrophomonas maltophilia, 1 Achromobacter xylosoxidans, 1 Campylobacter jejuni, 1 Aeromonas sobrio, 1 Capnocytophaga species, 1 Sphingomonas paucimobilis.