Table 1.

Patient baseline characteristics

N = 101
Age, median (range), y 58 (23-76) 
≥65 y, n (%) 24 (24) 
Male sex, n (%) 68 (67) 
Disease type, n (%)  
DLBCL 77 (76) 
PMBCL 8 (8) 
TFL 16 (16) 
Prognostic marker per central laboratory, n (%)  
HGBL – double hit 3 (3) 
HGBL – triple hit 1 (1) 
HGBL-NOS 2 (2) 
Double-expressor lymphoma 27 (27) 
No HGBL/tested negative 7 (7) 
N/A 2 (2) 
Not tested 59 (58) 
Previous therapies, n (%)  
ASCT 25 (25) 
Platinum based 90 (89) 
Response to most recent prior therapy, n (%)   
SD 13 (13) 
PD 67 (66) 
Lymphoma present in bone marrow, n (%) 8 (8) 
LDH > ULN, n (%) 85 (84) 
Sum of product diameters, median (range), mm2 3723 (171-23 297) 
N = 101
Age, median (range), y 58 (23-76) 
≥65 y, n (%) 24 (24) 
Male sex, n (%) 68 (67) 
Disease type, n (%)  
DLBCL 77 (76) 
PMBCL 8 (8) 
TFL 16 (16) 
Prognostic marker per central laboratory, n (%)  
HGBL – double hit 3 (3) 
HGBL – triple hit 1 (1) 
HGBL-NOS 2 (2) 
Double-expressor lymphoma 27 (27) 
No HGBL/tested negative 7 (7) 
N/A 2 (2) 
Not tested 59 (58) 
Previous therapies, n (%)  
ASCT 25 (25) 
Platinum based 90 (89) 
Response to most recent prior therapy, n (%)   
SD 13 (13) 
PD 67 (66) 
Lymphoma present in bone marrow, n (%) 8 (8) 
LDH > ULN, n (%) 85 (84) 
Sum of product diameters, median (range), mm2 3723 (171-23 297) 

ASCT, autologous SCT; HGBL, high-grade B-cell lymphoma; LDH, lactate dehydrogenase; N/A, not available; NOS, not otherwise specified; PD, progressive disease; PMBCL, primary mediastinal B-cell lymphoma; SD, stable disease; TFL, transformed follicular lymphoma; ULN, upper limit of normal.

Patients included those who did not relapse after ASCT.

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