Univariate and multivariate analysis of clinicopathologic variables in BPDCN
| Univariate analysis . | ||||
|---|---|---|---|---|
| . | . | 95% CI of HR . | . | |
| Factor . | HR . | Lower . | Upper . | P value . |
| TET2 Truncating mt | 4.653 | 1.927 | 11.234 | .0006 |
| SL401 (YES) | 2.212 | 0.76 | 6.439 | .145 |
| Ven (YES) | 0.831 | 0.373 | 1.852 | .651 |
| Age_at_Dx | 1.052 | 1.02 | 1.085 | .001 |
| Cyto (complex) | 0.899 | 0.364 | 2.223 | .818 |
| Cyto (diploid) | 1.307 | 0.554 | 3.083 | .541 |
| Cyto (other) | 1.696 | 0.396 | 7.261 | .507 |
| Univariate analysis . | ||||
|---|---|---|---|---|
| . | . | 95% CI of HR . | . | |
| Factor . | HR . | Lower . | Upper . | P value . |
| TET2 Truncating mt | 4.653 | 1.927 | 11.234 | .0006 |
| SL401 (YES) | 2.212 | 0.76 | 6.439 | .145 |
| Ven (YES) | 0.831 | 0.373 | 1.852 | .651 |
| Age_at_Dx | 1.052 | 1.02 | 1.085 | .001 |
| Cyto (complex) | 0.899 | 0.364 | 2.223 | .818 |
| Cyto (diploid) | 1.307 | 0.554 | 3.083 | .541 |
| Cyto (other) | 1.696 | 0.396 | 7.261 | .507 |
| Multivariate analysis . | ||||
|---|---|---|---|---|
| . | . | 95% CI of HR . | . | |
| Factor . | HR . | Lower . | Upper . | P value . |
| SL401 (YES) | 2.038 | 0.627 | 6.627 | .237 |
| Ven (YES) | 0.568 | 0.224 | 1.44 | .233 |
| Age_at_Dx | 1.023 | 0.986 | 1.06 | .227 |
| TET2 Truncating mt | 3.452 | 1.109 | 10.742 | .032 |
| Cyto (Complex) | 11.251 | 0.556 | 227.749 | .115 |
| Cyto (Diploid) | 9.669 | 0.557 | 167.769 | .119 |
| Cyto (Other) | 2.434 | 0.311 | 19.064 | .397 |
| Multivariate analysis . | ||||
|---|---|---|---|---|
| . | . | 95% CI of HR . | . | |
| Factor . | HR . | Lower . | Upper . | P value . |
| SL401 (YES) | 2.038 | 0.627 | 6.627 | .237 |
| Ven (YES) | 0.568 | 0.224 | 1.44 | .233 |
| Age_at_Dx | 1.023 | 0.986 | 1.06 | .227 |
| TET2 Truncating mt | 3.452 | 1.109 | 10.742 | .032 |
| Cyto (Complex) | 11.251 | 0.556 | 227.749 | .115 |
| Cyto (Diploid) | 9.669 | 0.557 | 167.769 | .119 |
| Cyto (Other) | 2.434 | 0.311 | 19.064 | .397 |
Age_at_Dx, age at diagnosis; CI, confidence interval; Cyto, cytogenetics; mt, mutation; SL401, taxograxofusp; Ven, venetoclax.
Significant p-values < 0.05 are shown in bold.