Table 1.

BTK mutations detected in a cohort of patients with disease progression during BTKi treatment

Number of patients carrying the mutationsP
Ibrutinib-treated patients (n = 24)Zanubrutinib-treated patients (n =13)Total
Cys481 codon mutations 24 10 34 .03 
Leu528Trp .001 
Number of patients carrying the mutationsP
Ibrutinib-treated patients (n = 24)Zanubrutinib-treated patients (n =13)Total
Cys481 codon mutations 24 10 34 .03 
Leu528Trp .001 
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