Response by 2018 iwCLL criteria and MRD status via flow cytometry undetectable is defined as <1 in 10 000 CLL cells detected via flow cytometry
| Response . | Cycle 12 (n = 38) . | Cycle 24 (n = 32) . | MRD status . |
|---|---|---|---|
| CR | 1 (2.6%; 95% CI, 0.07-13.8) | - | Undetectable in PB and BM |
| PR | 26 (68.4%; 95% CI, 51.4-82.5) | 23 (71.9%; 95% CI, 53.3-86.3) | |
| PR lymphocytosis | 11 (28.9%; 95% CI, 15.4-45.9) | 7 (21.9%; 95% CI, 9.3-40.0) | |
| Progressive disease | - | 2 (6.3%; 95% CI, 0.8-20.8) |
| Response . | Cycle 12 (n = 38) . | Cycle 24 (n = 32) . | MRD status . |
|---|---|---|---|
| CR | 1 (2.6%; 95% CI, 0.07-13.8) | - | Undetectable in PB and BM |
| PR | 26 (68.4%; 95% CI, 51.4-82.5) | 23 (71.9%; 95% CI, 53.3-86.3) | |
| PR lymphocytosis | 11 (28.9%; 95% CI, 15.4-45.9) | 7 (21.9%; 95% CI, 9.3-40.0) | |
| Progressive disease | - | 2 (6.3%; 95% CI, 0.8-20.8) |
Detectable is ≥1 in 10 000 CLL cells.
BM, bone marrow; CI, confidence interval; PB, peripheral blood; PR, partial response.