Table 1.

Demographic and clinical data for controls as well as patients with lymphoid and myeloid neoplasms

VariableHealthy controls,
n = 91 
Lymphoid neoplasms,
n = 42 
Myeloid neoplasms,
n = 88 
P value 
Age (y) 52 (38; 62) 66 (48; 74) 62 (52; 67) < .001 
Sex    .033 
Female 54 (59%) 17 (40%) 37 (42%)  
Male 37 (41%) 25 (60%) 51 (58%)  
WBC 6.10 (5.30; 7.75) 5.40 (4.10; 6.77) 6.00 (4.27; 8.38) .2 
SARS-CoV-2 vaccination scheme    .07 
Vector based 13 (14%) 4 (9.5%) 11 (12%)  
2× mRNA-based 62 (68%) 37 (88%) 69 (78%)  
Only one  16 (18%) 1 (2.4%) 8 (9.1%)  
Prior SARS-CoV-2 infection    .7 
Yes 3 (3.3%) 1 (2.4%) 5 (5.7%)  
No 88 (97%) 41 (98%) 83 (94%)  
Current cancer treatment    .04 (lymphoid vs myeloid) 
Yes 0 (0%) 21 (50%) 60 (68%)  
No 91 (100%) 21 (50%) 28 (32%)  
VariableHealthy controls,
n = 91 
Lymphoid neoplasms,
n = 42 
Myeloid neoplasms,
n = 88 
P value 
Age (y) 52 (38; 62) 66 (48; 74) 62 (52; 67) < .001 
Sex    .033 
Female 54 (59%) 17 (40%) 37 (42%)  
Male 37 (41%) 25 (60%) 51 (58%)  
WBC 6.10 (5.30; 7.75) 5.40 (4.10; 6.77) 6.00 (4.27; 8.38) .2 
SARS-CoV-2 vaccination scheme    .07 
Vector based 13 (14%) 4 (9.5%) 11 (12%)  
2× mRNA-based 62 (68%) 37 (88%) 69 (78%)  
Only one  16 (18%) 1 (2.4%) 8 (9.1%)  
Prior SARS-CoV-2 infection    .7 
Yes 3 (3.3%) 1 (2.4%) 5 (5.7%)  
No 88 (97%) 41 (98%) 83 (94%)  
Current cancer treatment    .04 (lymphoid vs myeloid) 
Yes 0 (0%) 21 (50%) 60 (68%)  
No 91 (100%) 21 (50%) 28 (32%)  

WBC, white blood cell count.

Median (Q1 and Q3); n (%).

Kruskal-Wallis rank sum test; Fisher exact test.

Summarizes in-label Ad26.COV2.S (Janssen) and off-label single-shot immunization using either mRNA vaccine.

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