Table 1. Cellular and plasma cGVHD... | American Society of Hematology

Table 1.

Cellular and plasma cGVHD markers with a selection frequency greater than or equal to 0.99 in the diagnostic cGVHD classifier

Cell type or plasma protein	Immune phenotype or plasma protein	Selection frequency
NKreg noncytolytic	CD56^bright Perforin⁻	0.999
NKreg noncytolytic	CD56^bright Granzyme B⁻	0.999
Naïve Th cells	CD4⁺ CD45RA⁺ PD1⁻	1
Naïve Th cells	CD4⁺ CD45RA⁺ CCR7⁺	1
Naïve Th cells	CD4⁺ CD45RA⁺ CD27⁺	1
Naïve Th cells (RTE)	CD4⁺ CD45RA⁺ CD31⁺	1
Naïve Tc cells	CD8⁺ CD45RA⁺ CCR7⁺	0.994
Naïve Treg cells	CD45RA⁺ PD1⁻ Treg	1
Naïve Treg cells (RTE)	CD45RA⁺ CD31⁺ Treg	1
Plasma protein	CXCL9	1
Plasma protein	CXCL10 (IP10)	0.998
Plasma protein	CXCL11	1
Plasma protein	ICAM-1	1
Plasma protein	TIM-3	0.999
Plasma protein	ST2	1

Cell type or plasma protein	Immune phenotype or plasma protein	Selection frequency
NKreg noncytolytic	CD56^bright Perforin⁻	0.999
NKreg noncytolytic	CD56^bright Granzyme B⁻	0.999
Naïve Th cells	CD4⁺ CD45RA⁺ PD1⁻	1
Naïve Th cells	CD4⁺ CD45RA⁺ CCR7⁺	1
Naïve Th cells	CD4⁺ CD45RA⁺ CD27⁺	1
Naïve Th cells (RTE)	CD4⁺ CD45RA⁺ CD31⁺	1
Naïve Tc cells	CD8⁺ CD45RA⁺ CCR7⁺	0.994
Naïve Treg cells	CD45RA⁺ PD1⁻ Treg	1
Naïve Treg cells (RTE)	CD45RA⁺ CD31⁺ Treg	1
Plasma protein	CXCL9	1
Plasma protein	CXCL10 (IP10)	0.998
Plasma protein	CXCL11	1
Plasma protein	ICAM-1	1
Plasma protein	TIM-3	0.999
Plasma protein	ST2	1

RTE, recent thymic emigrant.