Univariable analysis of the cumulative incidence of relapse and leukemia-specific mortality based on MRDpre and MRDpost levels
MRDpre level (N = 122) . | Cumulative incidence of relapse . | Leukemia-specific mortality . | ||
---|---|---|---|---|
HR (95% CI) . | P value . | HR (95% CI) . | P value . | |
Undetectable | 1 | 1 | ||
Low (<10–4) | 3.56 (1.39-9.15) | .01 | 2.90 (0.80-10.52) | .10 |
High (>10–4 to ≤10–3) | 2.89 (0.75-11.20) | .12 | 3.37 (0.61-18.69) | .17 |
Very high (>10–3) | 6.98 (2.12-22.91) | .0014 | 3.34 (0.41-27.55) | .26 |
MRDpre level (N = 122) . | Cumulative incidence of relapse . | Leukemia-specific mortality . | ||
---|---|---|---|---|
HR (95% CI) . | P value . | HR (95% CI) . | P value . | |
Undetectable | 1 | 1 | ||
Low (<10–4) | 3.56 (1.39-9.15) | .01 | 2.90 (0.80-10.52) | .10 |
High (>10–4 to ≤10–3) | 2.89 (0.75-11.20) | .12 | 3.37 (0.61-18.69) | .17 |
Very high (>10–3) | 6.98 (2.12-22.91) | .0014 | 3.34 (0.41-27.55) | .26 |
MRDpostlevel (N = 139) . | HR (95% CI) . | P value . | HR (95% CI) . | P value . |
---|---|---|---|---|
Undetectable | 1 | 1 | ||
Detectable | 6.31 (4.56-8.74) | <.0001 | 7.74 (4.86-12.32) | <.0001 |
MRDpostlevel (N = 139) . | HR (95% CI) . | P value . | HR (95% CI) . | P value . |
---|---|---|---|---|
Undetectable | 1 | 1 | ||
Detectable | 6.31 (4.56-8.74) | <.0001 | 7.74 (4.86-12.32) | <.0001 |