Patients and transplantation characteristics
Patients characteristics . | N = 46 (%) . |
---|---|
Age (y) | |
Median | 60 |
Range | 18-74 |
Sex | |
Male | 25 (54) |
Female | 21 (46) |
Race or ethnicity | |
Caucasian | 27 (59) |
Hispanic | 12 (26) |
African American | 5 (11) |
Asian | 2 (4) |
HCT-CI | |
0 | 17 (37) |
1-2 | 19 (41) |
≥3 | 10 (22) |
Disease | |
AML | 16 (35) |
MDS | 7 (15) |
ALL | 16 (35) |
MF | 1 (2) |
T-cell NHL | 5 (11) |
BPDCN | 1 (2) |
Disease-risk index | |
Low | 2 (4) |
Intermediate | 29 (63) |
High | 14 (30) |
N/A | 1 (2) |
Disease status | |
Complete remission | 35 (76) |
Active disease | 10 (22) |
Unknown | 1 (2) |
CMV status (D/R) | |
−/− | 13 (28) |
+/− | 2 (4) |
−/+ | 9 (20) |
+/+ | 22 (48) |
Conditioning regimen | |
FluCy TBI (NMA) | 16 (35) |
FluCyBu TBI (RIC) | 5 (11) |
FluCyBu (MA) | 14 (30) |
Flu TBI (MA) | 11 (24) |
CD34+cell dose (106cells per kg) | |
Median | 6.5 |
Range | 2.6-10.3 |
Patients characteristics . | N = 46 (%) . |
---|---|
Age (y) | |
Median | 60 |
Range | 18-74 |
Sex | |
Male | 25 (54) |
Female | 21 (46) |
Race or ethnicity | |
Caucasian | 27 (59) |
Hispanic | 12 (26) |
African American | 5 (11) |
Asian | 2 (4) |
HCT-CI | |
0 | 17 (37) |
1-2 | 19 (41) |
≥3 | 10 (22) |
Disease | |
AML | 16 (35) |
MDS | 7 (15) |
ALL | 16 (35) |
MF | 1 (2) |
T-cell NHL | 5 (11) |
BPDCN | 1 (2) |
Disease-risk index | |
Low | 2 (4) |
Intermediate | 29 (63) |
High | 14 (30) |
N/A | 1 (2) |
Disease status | |
Complete remission | 35 (76) |
Active disease | 10 (22) |
Unknown | 1 (2) |
CMV status (D/R) | |
−/− | 13 (28) |
+/− | 2 (4) |
−/+ | 9 (20) |
+/+ | 22 (48) |
Conditioning regimen | |
FluCy TBI (NMA) | 16 (35) |
FluCyBu TBI (RIC) | 5 (11) |
FluCyBu (MA) | 14 (30) |
Flu TBI (MA) | 11 (24) |
CD34+cell dose (106cells per kg) | |
Median | 6.5 |
Range | 2.6-10.3 |
AML, acute myeloid leukemia; ALL, acute lymphoblastic leukemia; BPDCN, blastic plasmacytoid dendritic cell neoplasm; Bu, busulfan; CMV, cytomegalovirus; D/R, donor/recipient; Flu, fludarabine; MA, myeloablative; MDS, myelodysplastic syndrome; MF, myelofibrosis; NHL, non-Hodgkin lymphoma.