Multivariable analysis of the prognostic impact of LSC17 score on DFS and OS in the ALFA-0702 cohort
| . | DFS . | OS . | ||
|---|---|---|---|---|
| HR (95% CI) . | P value . | HR (95% CI) . | P value . | |
| LSC17 status | ||||
| LSC17 low | 1 | 1 | ||
| LSC17 high | 1.36 (1.002-1.86) | .048 | 1.27 (0.94-1.72) | .11 |
| Age (per 10-y of age) | 1.20 (1.05-1.37) | .008 | 1.28 (1.12-1.46) | .0003 |
| Log10(WBC) | 1.38 (1.10-1.74) | .006 | 1.48 (1.19-1.83) | .0004 |
| ELN 2022 risk | ||||
| Favorable | 1 | 1 | ||
| Intermediate | 1.78 (1.19-2.66) | .005 | 2.85 (1.80-4.51) | < .0001 |
| Adverse | 2.31 (1.54-3.46) | < .0001 | 3.93 (2.49-6.21) | < .0001 |
| . | DFS . | OS . | ||
|---|---|---|---|---|
| HR (95% CI) . | P value . | HR (95% CI) . | P value . | |
| LSC17 status | ||||
| LSC17 low | 1 | 1 | ||
| LSC17 high | 1.36 (1.002-1.86) | .048 | 1.27 (0.94-1.72) | .11 |
| Age (per 10-y of age) | 1.20 (1.05-1.37) | .008 | 1.28 (1.12-1.46) | .0003 |
| Log10(WBC) | 1.38 (1.10-1.74) | .006 | 1.48 (1.19-1.83) | .0004 |
| ELN 2022 risk | ||||
| Favorable | 1 | 1 | ||
| Intermediate | 1.78 (1.19-2.66) | .005 | 2.85 (1.80-4.51) | < .0001 |
| Adverse | 2.31 (1.54-3.46) | < .0001 | 3.93 (2.49-6.21) | < .0001 |
Bold values indicate significant P < 0.05.