Characteristics of 4023 patients with MPN, 2010-2017
| . | Overall, n (%) . | Hydroxyurea, n (%) . | ||
|---|---|---|---|---|
| Yes . | No . | P . | ||
| Total | 4023 | 2683 | 1340 | — |
| Type of MPN | ||||
| PV | 1688 (42.0) | 1017 (37.9) | 671 (50.1) | <.01 |
| ET | 1976 (49.1) | 1548 (57.7) | 428 (31.9) | — |
| MF | 359 (8.9) | 118 (4.4) | 241 (18.0) | — |
| Age, y | ||||
| Median (IQR) | 77 (71-83) | 76 (71-83) | 77 (72-83) | — |
| 66-69 | 683 (17.0) | 412 (15.4) | 271 (20.2) | <.01 |
| 70-74 | 927 (23.0) | 601 (22.4) | 326 (24.3) | — |
| 75-79 | 845 (21.0) | 594 (22.1) | 251 (18.7) | — |
| 80-84 | 769 (19.1) | 536 (20.0) | 233 (17.4) | — |
| ≥85 | 799 (19.9) | 540 (20.1) | 259 (19.3) | — |
| Sex | ||||
| Female | 2468 (61.3) | 1771 (66.0) | 697 (52.0) | <.01 |
| Male | 1555 (38.7) | 912 (34.0) | 643 (48.0) | — |
| Race | ||||
| White | 3469 (86.2) | 2323 (86.6) | 1146 (85.5) | .36 |
| Other | 554 (13.8) | 360 (13.4) | 194 (14.5) | — |
| Marital status | ||||
| Single | 1341 (33.3) | 897 (33.4) | 444 (33.1) | .26 |
| Married | 2362 (58.7) | 1560 (58.1) | 802 (59.9) | — |
| Unknown | 320 (8.0) | 226 (8.4) | 94 (7.0) | — |
| Region | ||||
| Northeast | 1794 (44.6) | 1168 (43.5) | 626 (46.7) | <.01 |
| Midwest | 370 (9.2) | 275 (10.2) | 95 (7.1) | — |
| South | 753 (18.7) | 468 (17.4) | 285 (21.3) | — |
| West | 1106 (27.5) | 772 (28.8) | 334 (24.9) | — |
| Elixhauser Comorbidity Index | ||||
| 0 | 506 (12.6) | 344 (12.8) | 162 (12.1) | <.01 |
| 1-2 | 1609 (40.0) | 1141 (42.5) | 468 (34.9) | — |
| ≥3 | 1908 (47.4) | 1198 (44.7) | 710 (53.0) | — |
| Previous cancer | ||||
| No | 3059 (76.0) | 2046 (76.3) | 1013 (75.6) | .64 |
| Yes | 964 (24.0) | 637 (23.7) | 327 (24.4) | — |
| Disability | ||||
| No | 3563 (88.6) | 2392 (89.2) | 1171 (87.4) | .10 |
| Yes | 460 (11.4) | 291 (10.8) | 169 (12.6) | — |
| Yost index | ||||
| Fifth quintile (highest SES) | — | 899 (33.5) | 426 (31.8) | .22 |
| Fourth quintile | 1325 (32.9) | 551 (20.5) | 277 (20.7) | — |
| Third quintile | 828 (20.6) | 424 (15.8) | 223 (16.6) | — |
| Second quintile | 647 (16.1) | 418 (15.6) | 200 (14.9) | — |
| First quintile (lowest SES) | 618 (15.4) | 267 (10.0) | 164 (12.2) | — |
| Unknown | 431 (10.7) | 124 (4.6) | 50 (3.7) | — |
| State buy-in | ||||
| No | 3355 (83.4) | 2263 (84.3) | 1092 (81.5) | .02 |
| Yes | 668 (16.6) | 420 (15.7) | 248 (18.5) | — |
| . | Overall, n (%) . | Hydroxyurea, n (%) . | ||
|---|---|---|---|---|
| Yes . | No . | P . | ||
| Total | 4023 | 2683 | 1340 | — |
| Type of MPN | ||||
| PV | 1688 (42.0) | 1017 (37.9) | 671 (50.1) | <.01 |
| ET | 1976 (49.1) | 1548 (57.7) | 428 (31.9) | — |
| MF | 359 (8.9) | 118 (4.4) | 241 (18.0) | — |
| Age, y | ||||
| Median (IQR) | 77 (71-83) | 76 (71-83) | 77 (72-83) | — |
| 66-69 | 683 (17.0) | 412 (15.4) | 271 (20.2) | <.01 |
| 70-74 | 927 (23.0) | 601 (22.4) | 326 (24.3) | — |
| 75-79 | 845 (21.0) | 594 (22.1) | 251 (18.7) | — |
| 80-84 | 769 (19.1) | 536 (20.0) | 233 (17.4) | — |
| ≥85 | 799 (19.9) | 540 (20.1) | 259 (19.3) | — |
| Sex | ||||
| Female | 2468 (61.3) | 1771 (66.0) | 697 (52.0) | <.01 |
| Male | 1555 (38.7) | 912 (34.0) | 643 (48.0) | — |
| Race | ||||
| White | 3469 (86.2) | 2323 (86.6) | 1146 (85.5) | .36 |
| Other | 554 (13.8) | 360 (13.4) | 194 (14.5) | — |
| Marital status | ||||
| Single | 1341 (33.3) | 897 (33.4) | 444 (33.1) | .26 |
| Married | 2362 (58.7) | 1560 (58.1) | 802 (59.9) | — |
| Unknown | 320 (8.0) | 226 (8.4) | 94 (7.0) | — |
| Region | ||||
| Northeast | 1794 (44.6) | 1168 (43.5) | 626 (46.7) | <.01 |
| Midwest | 370 (9.2) | 275 (10.2) | 95 (7.1) | — |
| South | 753 (18.7) | 468 (17.4) | 285 (21.3) | — |
| West | 1106 (27.5) | 772 (28.8) | 334 (24.9) | — |
| Elixhauser Comorbidity Index | ||||
| 0 | 506 (12.6) | 344 (12.8) | 162 (12.1) | <.01 |
| 1-2 | 1609 (40.0) | 1141 (42.5) | 468 (34.9) | — |
| ≥3 | 1908 (47.4) | 1198 (44.7) | 710 (53.0) | — |
| Previous cancer | ||||
| No | 3059 (76.0) | 2046 (76.3) | 1013 (75.6) | .64 |
| Yes | 964 (24.0) | 637 (23.7) | 327 (24.4) | — |
| Disability | ||||
| No | 3563 (88.6) | 2392 (89.2) | 1171 (87.4) | .10 |
| Yes | 460 (11.4) | 291 (10.8) | 169 (12.6) | — |
| Yost index | ||||
| Fifth quintile (highest SES) | — | 899 (33.5) | 426 (31.8) | .22 |
| Fourth quintile | 1325 (32.9) | 551 (20.5) | 277 (20.7) | — |
| Third quintile | 828 (20.6) | 424 (15.8) | 223 (16.6) | — |
| Second quintile | 647 (16.1) | 418 (15.6) | 200 (14.9) | — |
| First quintile (lowest SES) | 618 (15.4) | 267 (10.0) | 164 (12.2) | — |
| Unknown | 431 (10.7) | 124 (4.6) | 50 (3.7) | — |
| State buy-in | ||||
| No | 3355 (83.4) | 2263 (84.3) | 1092 (81.5) | .02 |
| Yes | 668 (16.6) | 420 (15.7) | 248 (18.5) | — |