Within-patient variance and variance explained by antibodies in patients with temporarily decreased IR in pathfinder6
Model . | Within-patient variance . | Variance explained (%) . |
---|---|---|
Reference | 0.68 | 0 |
Only anti-PEG IgG | 0.28 | 58.4 |
Only anti-PEG IgM | 0.61 | 10.3 |
Only anti–N8-GP-binding | 0.58 | 14.2 |
Full model | 0.26 | 62.3 |
Model . | Within-patient variance . | Variance explained (%) . |
---|---|---|
Reference | 0.68 | 0 |
Only anti-PEG IgG | 0.28 | 58.4 |
Only anti-PEG IgM | 0.61 | 10.3 |
Only anti–N8-GP-binding | 0.58 | 14.2 |
Full model | 0.26 | 62.3 |
Temporarily decreased IR was defined as patients with an observation of 2 consecutive measurements of IR <0.6 (IU/dL)/(IU/kg) without inhibitors. Within-subject variance and variance explained were determined by coefficient of determination and R2 values.