Participant characteristics by cohort and presence of proteinuria
| . | OMG-SCD (N = 576) . | Walk-PHaSST (N = 502) . | P value . |
|---|---|---|---|
| Mean age, y (SD) | 33.89 (12.16) | 37.58 (12.62) | <10–4 |
| Proteinuria = Y | 38.22 (12.77) | 40.20 (12.96) | .26 |
| Proteinuria = N | 31.96 (11.48) | 36.86 (12.46) | <10–4 |
| % Female | 54.34 | 54.58 | .94 |
| Proteinuria = Y, % | 50.69 | 49.45 | .85 |
| Proteinuria = N, % | 55.21 | 55.35 | .97 |
| % Hb SS/Sβ0 | 84.55 | 72.46 | <10–4 |
| Proteinuria = Y, % | 91.67 | 83.52 | .06 |
| Proteinuria = N, % | 82.08 | 70.94 | 2 × 10–4 |
| Mean eGFR (SD) | 152.12 (67.26) | 148.66 (63.16) | .41 |
| Proteinuria = Y | 123.31 (66.25) | 137.56 (75.86) | .15 |
| Proteinuria = N | 164.77 (64.32) | 153.22 (58.45) | .01 |
| % eGFR < 60 mL/min per 1.73 m2, % | 9.07 | 7.49 | .37 |
| Proteinuria = Y, % | 21.93 | 18.89 | .59 |
| Proteinuria = N, % | 4.55 | 3.72 | .58 |
| % Proteinuria | 26.00 | 18.13 | .01 |
| . | OMG-SCD (N = 576) . | Walk-PHaSST (N = 502) . | P value . |
|---|---|---|---|
| Mean age, y (SD) | 33.89 (12.16) | 37.58 (12.62) | <10–4 |
| Proteinuria = Y | 38.22 (12.77) | 40.20 (12.96) | .26 |
| Proteinuria = N | 31.96 (11.48) | 36.86 (12.46) | <10–4 |
| % Female | 54.34 | 54.58 | .94 |
| Proteinuria = Y, % | 50.69 | 49.45 | .85 |
| Proteinuria = N, % | 55.21 | 55.35 | .97 |
| % Hb SS/Sβ0 | 84.55 | 72.46 | <10–4 |
| Proteinuria = Y, % | 91.67 | 83.52 | .06 |
| Proteinuria = N, % | 82.08 | 70.94 | 2 × 10–4 |
| Mean eGFR (SD) | 152.12 (67.26) | 148.66 (63.16) | .41 |
| Proteinuria = Y | 123.31 (66.25) | 137.56 (75.86) | .15 |
| Proteinuria = N | 164.77 (64.32) | 153.22 (58.45) | .01 |
| % eGFR < 60 mL/min per 1.73 m2, % | 9.07 | 7.49 | .37 |
| Proteinuria = Y, % | 21.93 | 18.89 | .59 |
| Proteinuria = N, % | 4.55 | 3.72 | .58 |
| % Proteinuria | 26.00 | 18.13 | .01 |
χ2 tests and generalized linear models were used to determine differences of percentages and means between OMG-SCD and Walk-PHaSST, respectively.
Hb, hemoglobin; N, no (negative); SD, standard deviation; Y, yes (positive).