Characteristics of the cohort of patient with iTTP
| Characteristics . | n . | % . |
|---|---|---|
| Total number of patients with iTTP | 83∗ | |
| Sex | ||
| Female | 61 | 73 |
| Male | 22 | 27 |
| Ethnicity | ||
| Caucasian | 83 | 100 |
| Observation time, d | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 468 (1, 56, 680, 782) | |
| Age at time of enrollment, y | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 49 (20, 39, 57, 86) | |
| Age at time of diagnosis of first acute iTTP episode, years† | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 38 (12, 27, 49, 85) | |
| Number of acute TTP episodes during study | 22 in 16 patients | |
| Patients enrolled during acute iTTP | 8 | |
| Initial diagnosis during study | 4 | |
| Relapse of iTTP | 4 | |
| Relapses during follow-up after enrollment | 14 | |
| Number of patients with iTTP in continued remission during study | 67 | |
| Number of all acute episodes per patient before enrollment into the study‡ | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 2 (0, 1, 3, 23) | |
| Risk factors for iTTP | ||
| Smoking | 17 | 20 |
| Overweight (BMI, 27-29.9)§ | 12 | 16 |
| Obesity (BMI >30)§ | 26 | 34 |
| Arterial hypertension | 28 | 31 |
| Type 1 diabetes mellitus | 1 | 1 |
| Type 2 diabetes mellitus | 11 | 13 |
| Characteristics . | n . | % . |
|---|---|---|
| Total number of patients with iTTP | 83∗ | |
| Sex | ||
| Female | 61 | 73 |
| Male | 22 | 27 |
| Ethnicity | ||
| Caucasian | 83 | 100 |
| Observation time, d | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 468 (1, 56, 680, 782) | |
| Age at time of enrollment, y | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 49 (20, 39, 57, 86) | |
| Age at time of diagnosis of first acute iTTP episode, years† | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 38 (12, 27, 49, 85) | |
| Number of acute TTP episodes during study | 22 in 16 patients | |
| Patients enrolled during acute iTTP | 8 | |
| Initial diagnosis during study | 4 | |
| Relapse of iTTP | 4 | |
| Relapses during follow-up after enrollment | 14 | |
| Number of patients with iTTP in continued remission during study | 67 | |
| Number of all acute episodes per patient before enrollment into the study‡ | ||
| Median (minimum, 25th percentile, 75th percentile, maximum) | 2 (0, 1, 3, 23) | |
| Risk factors for iTTP | ||
| Smoking | 17 | 20 |
| Overweight (BMI, 27-29.9)§ | 12 | 16 |
| Obesity (BMI >30)§ | 26 | 34 |
| Arterial hypertension | 28 | 31 |
| Type 1 diabetes mellitus | 1 | 1 |
| Type 2 diabetes mellitus | 11 | 13 |