Obstetrical outcomes for patients with relapsed lymphoma during pregnancy
| . | All patients N = 23 . | Patients who had antenatal therapy N = 5 . | Patients without treatment in pregnancy N = 18∗ . |
|---|---|---|---|
| Median GA at recurrence, wk | 20 (13-28) | 25 (20-30) | 19 (10-28) |
| Median GA at treatment, wk | NA | 26 (25-30) | NA |
| Median GA at delivery, wk | 36 wk (35-38) | 36 (33.5-36.5) | 36.5 (35.7-38) |
| Median birthweight, grams | 2777 (2493-3373) | 2784 (2315-3373) | 2769 (2585-3292) |
| Elective abortion | 3 (14) | 0 | 3 |
| Miscarriage | 1 (5) | 0 | 1 |
| Live birth | 18 (82) | 5 | 14 |
| Cesarian delivery | 6 (33) | 0 | 6 |
| ≥37 wk | 8 (42) | 2 | 6 |
| <37 wk | 10 (53) | 2 | 8 |
| <32 wk | 1 (5) | 1 | 0 |
| Clinically initiated PTD | 7 (64) | 2 | 6 |
| Postpartum hemorrhage | 0 | 0 | 0 |
| Chorioamnionitis | 0 | 0 | 0 |
| Endometritis | 1 | 0 | 1 |
| Transfusion of blood products | 0 | 0 | 0 |
| GDM | 2 | 0 | 2 |
| Preeclampsia | 1 | 0 | 1 |
| . | All patients N = 23 . | Patients who had antenatal therapy N = 5 . | Patients without treatment in pregnancy N = 18∗ . |
|---|---|---|---|
| Median GA at recurrence, wk | 20 (13-28) | 25 (20-30) | 19 (10-28) |
| Median GA at treatment, wk | NA | 26 (25-30) | NA |
| Median GA at delivery, wk | 36 wk (35-38) | 36 (33.5-36.5) | 36.5 (35.7-38) |
| Median birthweight, grams | 2777 (2493-3373) | 2784 (2315-3373) | 2769 (2585-3292) |
| Elective abortion | 3 (14) | 0 | 3 |
| Miscarriage | 1 (5) | 0 | 1 |
| Live birth | 18 (82) | 5 | 14 |
| Cesarian delivery | 6 (33) | 0 | 6 |
| ≥37 wk | 8 (42) | 2 | 6 |
| <37 wk | 10 (53) | 2 | 8 |
| <32 wk | 1 (5) | 1 | 0 |
| Clinically initiated PTD | 7 (64) | 2 | 6 |
| Postpartum hemorrhage | 0 | 0 | 0 |
| Chorioamnionitis | 0 | 0 | 0 |
| Endometritis | 1 | 0 | 1 |
| Transfusion of blood products | 0 | 0 | 0 |
| GDM | 2 | 0 | 2 |
| Preeclampsia | 1 | 0 | 1 |
GA, gestational age; GDM, gestational diabetes mellitus; NA, not applicable; PTD, preterm delivery.
Data are presented as number (percentage) or median (interquartile range).
Two patients with Hodgkin lymphoma conceived during multiagent ifosfamide-based chemotherapy during the first trimester (at 5 and 8 weeks), with 1 patient having an elective abortion and the other a miscarriage; 1 patient with high-tumor burden follicular lymphoma had an elective abortion at week 7, and 1 patient was found to be pregnant in the first trimester during the final radiation treatment.