Table 3.

Any-grade TRAEs reported in greater than or equal to 10% of patients who received treatment and grade 3/4 TRAEs in all patients with R/R PMBL who received treatment

Any-grade TRAEs reported in ≥ 10% patients who received treatment, and grade 3/4 TRAEs in any patients, n (%)Any gradeGrade 3/4
Total 25 (83.3) 16 (53.3) 
Neutropenia 14 (43.3) 13 (40.0) 
Pyrexia 9 (30.0) 1 (3.3) 
Arthralgia 6 (20.0) 
Thrombocytopenia 5 (16.7) 3 (10.0) 
Rash 5 (16.7) 1 (3.3) 
Peripheral sensory neuropathy 5 (16.7) 
Peripheral neuropathy 4 (13.3) 3 (10.0) 
Hyperthyroidism 4 (13.3) 
Decreased neutrophil count 2 (6.7) 2 (6.7) 
Colitis 1 (3.3) 1 (3.3) 
Immune-mediated hepatitis 1 (3.3) 1 (3.3) 
Maculopapular rash 1 (3.3) 1 (3.3) 
Any-grade TRAEs reported in ≥ 10% patients who received treatment, and grade 3/4 TRAEs in any patients, n (%)Any gradeGrade 3/4
Total 25 (83.3) 16 (53.3) 
Neutropenia 14 (43.3) 13 (40.0) 
Pyrexia 9 (30.0) 1 (3.3) 
Arthralgia 6 (20.0) 
Thrombocytopenia 5 (16.7) 3 (10.0) 
Rash 5 (16.7) 1 (3.3) 
Peripheral sensory neuropathy 5 (16.7) 
Peripheral neuropathy 4 (13.3) 3 (10.0) 
Hyperthyroidism 4 (13.3) 
Decreased neutrophil count 2 (6.7) 2 (6.7) 
Colitis 1 (3.3) 1 (3.3) 
Immune-mediated hepatitis 1 (3.3) 1 (3.3) 
Maculopapular rash 1 (3.3) 1 (3.3) 
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