Blood and bone marrow results
| Sample . | Patient 1 2012 . | Patient 1 2013 . | Normal range (female) . | Patient 2 2011 . | Patient 2 2014 . | Patient 2 2016 . | Normal range (male) . | Patient 2 mother (carrier) . |
|---|---|---|---|---|---|---|---|---|
| WBC (K/μL) | 2.54 | 2.22 | 3.98-10.04 | 2.5 | 2 | 2.64 | 4.23-9.07 | 5.41 |
| Hemoglobin (g/dL) | 12.9 | 10.7 | 11.2-15.7 | 13.6 | 13.5 | 12 | 13.7-17.5 | 13.9 |
| Platelet count (K/μL) | 202 | 167 | 173-369 | 178 | 219 | 243 | 161-347 | 258 |
| Neutrophils, absolute (K/μL) | 0.81 | 0.33 | 1.56-6.13 | 2 | 1 | 1.74 | 1.78-5.38 | 3.34 |
| Monocytes, absolute (K/μL) | 0.01 | 0.04 | 0.24-0.86 | 0 | 0.09 | 0.13 | 0.30-0.82 | 0.45 |
| CD3+ T cells, absolute (cells/μL) | 1663 | 1498 | 714-2266 | nd | 772 | 640 | 714-2266 | 998 |
| CD19+/CD20+ B cells, absolute (cells/μL) | 14 | 27 | 59-329 | nd | 9 | 6 | 61-321 | 213 |
| NK cells, absolute (cells/μL) | 10 | 22 | 126-729 | nd | 126 | 93 | 126-729 | 150 |
| Trisomy 8 (%) | 70 to <80 | 85 | 0 | 50 | 85 | 80 | 0 | 0 |
| Bone marrow cellularity (%) | 5-10 | 5-10 | 60-70 | 15-25 | 25 | 30 | 60-70 | 30-40∗ |
| Sample . | Patient 1 2012 . | Patient 1 2013 . | Normal range (female) . | Patient 2 2011 . | Patient 2 2014 . | Patient 2 2016 . | Normal range (male) . | Patient 2 mother (carrier) . |
|---|---|---|---|---|---|---|---|---|
| WBC (K/μL) | 2.54 | 2.22 | 3.98-10.04 | 2.5 | 2 | 2.64 | 4.23-9.07 | 5.41 |
| Hemoglobin (g/dL) | 12.9 | 10.7 | 11.2-15.7 | 13.6 | 13.5 | 12 | 13.7-17.5 | 13.9 |
| Platelet count (K/μL) | 202 | 167 | 173-369 | 178 | 219 | 243 | 161-347 | 258 |
| Neutrophils, absolute (K/μL) | 0.81 | 0.33 | 1.56-6.13 | 2 | 1 | 1.74 | 1.78-5.38 | 3.34 |
| Monocytes, absolute (K/μL) | 0.01 | 0.04 | 0.24-0.86 | 0 | 0.09 | 0.13 | 0.30-0.82 | 0.45 |
| CD3+ T cells, absolute (cells/μL) | 1663 | 1498 | 714-2266 | nd | 772 | 640 | 714-2266 | 998 |
| CD19+/CD20+ B cells, absolute (cells/μL) | 14 | 27 | 59-329 | nd | 9 | 6 | 61-321 | 213 |
| NK cells, absolute (cells/μL) | 10 | 22 | 126-729 | nd | 126 | 93 | 126-729 | 150 |
| Trisomy 8 (%) | 70 to <80 | 85 | 0 | 50 | 85 | 80 | 0 | 0 |
| Bone marrow cellularity (%) | 5-10 | 5-10 | 60-70 | 15-25 | 25 | 30 | 60-70 | 30-40∗ |
Peripheral blood and bone marrow characteristics in patients 1 and 2 with MonoMAC.
Blood cell counts and bone marrow cytogenetics for patient 1 before bone marrow transplant (BMT), and patient 2, 5 and 2 years before and just before BMT. The asymptomatic carrier mother for patient 2 is also shown. The NIH Clinical Center normal ranges for adult female (patient 1) and adult male (patient 2) are given.
nd, not defined.
Indicates normal for age.