Table 2.

Proportions and timing of CAR-T–associated neurotoxicity

Neurotoxicity, CTCAE version 5.0Patients who were evaluable (n = 20)
Rating by CAR-T day 30  
Any grade, n (%) 10 (50)  
Grade ≥3, n (%) 5 (25) 
Median event duration, d (range)  
Any grade 24 (8-39)  
Grade ≥3 7 (2-28) 
Neurotoxicity, CTCAE version 5.0Patients who were evaluable (n = 20)
Rating by CAR-T day 30  
Any grade, n (%) 10 (50)  
Grade ≥3, n (%) 5 (25) 
Median event duration, d (range)  
Any grade 24 (8-39)  
Grade ≥3 7 (2-28) 

CTCAE, Common Terminology Criteria for Adverse Events.

Value is unadjusted for stage 1 analysis.

Event duration was calculated from the onset of the first CAR-T neurotoxicity event to the end date of the last CAR-T neurotoxicity event.

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