Risk factors of NRM at lymphodepletion by multivariate analysis
| Parameter . | Odds ratio estimate . | Lower 95% CI limit for odds ratio . | Upper 95% CI limit for odds ratio . |
|---|---|---|---|
| Age, y, ≥65, yes vs no | 1.033 | 0.992 | 1.075 |
| Diabetes, yes vs no | 4.417 | 1.651 | 11.819 |
| ECOG PS of ≥2 at lymphodepletion, yes vs no | 2.354 | 0.607 | 9.126 |
| Platelets < 50 G/L at lymphodepletion, yes vs no | 1.133 | 0.446 | 2.878 |
| Elevated ferritin level at lymphodepletion, yes vs no | 2.716 | 1.003 | 7.350 |
| C-reactive protein level > 30 mg/L at lymphodepletion, yes vs no | 1.246 | 0.399 | 3.892 |
| Parameter . | Odds ratio estimate . | Lower 95% CI limit for odds ratio . | Upper 95% CI limit for odds ratio . |
|---|---|---|---|
| Age, y, ≥65, yes vs no | 1.033 | 0.992 | 1.075 |
| Diabetes, yes vs no | 4.417 | 1.651 | 11.819 |
| ECOG PS of ≥2 at lymphodepletion, yes vs no | 2.354 | 0.607 | 9.126 |
| Platelets < 50 G/L at lymphodepletion, yes vs no | 1.133 | 0.446 | 2.878 |
| Elevated ferritin level at lymphodepletion, yes vs no | 2.716 | 1.003 | 7.350 |
| C-reactive protein level > 30 mg/L at lymphodepletion, yes vs no | 1.246 | 0.399 | 3.892 |
Logistic regression for the prediction of NRM comparing the overall NRM population with patients alive without progression at 1 year after CAR T-cell infusion.