Table 2.

Univariable and multivariable analysis of factors at diagnosis of SBP that predict for shorter TTP to MM

VariableTTP to MM
UnivariableMultivariable 
Hazard ratioP valueHazard ratioP value
Minimal marrow involvement 1.81 (1.10-2.99) .020 0.72 (0.23-2.22) .570 
Abnormal sFLC ratio 2.26 (1.16-4.39) .011 1.48 (0.63-3.52) .370 
Presence of HR FISH cytogenetics 3.23 (1.66-6.27) .0006 5.88 (2.47-14.0) <.001 
VariableTTP to MM
UnivariableMultivariable 
Hazard ratioP valueHazard ratioP value
Minimal marrow involvement 1.81 (1.10-2.99) .020 0.72 (0.23-2.22) .570 
Abnormal sFLC ratio 2.26 (1.16-4.39) .011 1.48 (0.63-3.52) .370 
Presence of HR FISH cytogenetics 3.23 (1.66-6.27) .0006 5.88 (2.47-14.0) <.001 

The boldface P values are statistically significant at P < .05.

Multivariate model included 49 patients with 31 events.

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