Laboratory findings in the coagulopathies of critical care
| Condition . | PT . | aPPT . | Fibrinogen levels . | D-dimer . | Bleeding time . | Platelet count . | Film comments . |
|---|---|---|---|---|---|---|---|
| Liver failure, early | Prolonged | Unaffected | Unaffected | Unaffected | Unaffected | Unaffected | |
| Liver failure, end stage | Prolonged | Prolonged | Low | Increased | Prolonged | Decreased | |
| Uremia | Unaffected | Unaffected | Unaffected | Unaffected | Prolonged | Unaffected | |
| Disseminated intravascular coagulation | Prolonged | Prolonged | Low | Increased | Prolonged | Decreased | Fragmented red cells |
| Thrombotic thrombocytopenic purpura | Unaffected | Unaffected | Unaffected | Unaffected | Prolonged | Very low | Fragmented red cells |
| Hyperfibrinolysis | Prolonged | Prolonged | Low | Very high | Possibly prolonged | Unaffected |
| Condition . | PT . | aPPT . | Fibrinogen levels . | D-dimer . | Bleeding time . | Platelet count . | Film comments . |
|---|---|---|---|---|---|---|---|
| Liver failure, early | Prolonged | Unaffected | Unaffected | Unaffected | Unaffected | Unaffected | |
| Liver failure, end stage | Prolonged | Prolonged | Low | Increased | Prolonged | Decreased | |
| Uremia | Unaffected | Unaffected | Unaffected | Unaffected | Prolonged | Unaffected | |
| Disseminated intravascular coagulation | Prolonged | Prolonged | Low | Increased | Prolonged | Decreased | Fragmented red cells |
| Thrombotic thrombocytopenic purpura | Unaffected | Unaffected | Unaffected | Unaffected | Prolonged | Very low | Fragmented red cells |
| Hyperfibrinolysis | Prolonged | Prolonged | Low | Very high | Possibly prolonged | Unaffected |