Vascular, cardiac, and pulmonary function in survivors and controls at the time of neurocognitive testing
| Test . | Survivors . | Controls . | P value∗ . |
|---|---|---|---|
| Mean (SD) . | Mean (SD) . | ||
| Pulmonary function test | |||
| FEV1 (% predicted) | 82.69 (15.95) | 96.23 (13.31) | <.001 |
| FEV1/FVC (%) | 0.99 (0.09) | 1.00 (0.08) | .240 |
| TLC (% predicted) | 87.27 (15.33) | 98.97 (12.89) | <.001 |
| DLCOcor (% predicted) | 83.31 (16.70) | 98.03 (14.93) | <.001 |
| Cardiac function test | |||
| Ejection fraction (3D ECHO) (%) | 0.56 (0.06) | 0.60 (0.05) | <.001 |
| GLS (%) | −18.30 (2.88) | −20.37 (2.24) | <.001 |
| Vascular studies | |||
| Pulse wave velocity (m/s) | 6.89 (1.70) | 7.24 (4.04) | .300 |
| Large artery elasticity (mL/mm Hg) | 17.44 (6.03) | 18.23 (5.01) | .060 |
| SAE (mL/mm Hg) | 6.94 (3.39) | 8.25 (3.43) | <.001 |
| Systolic blood pressure (mm Hg) | 124.75 (15.94) | 126.02 (12.51) | .410 |
| Diastolic blood pressure (mm Hg) | 74.34 (10.55) | 76.23 (9.87) | .078 |
| Test . | Survivors . | Controls . | P value∗ . |
|---|---|---|---|
| Mean (SD) . | Mean (SD) . | ||
| Pulmonary function test | |||
| FEV1 (% predicted) | 82.69 (15.95) | 96.23 (13.31) | <.001 |
| FEV1/FVC (%) | 0.99 (0.09) | 1.00 (0.08) | .240 |
| TLC (% predicted) | 87.27 (15.33) | 98.97 (12.89) | <.001 |
| DLCOcor (% predicted) | 83.31 (16.70) | 98.03 (14.93) | <.001 |
| Cardiac function test | |||
| Ejection fraction (3D ECHO) (%) | 0.56 (0.06) | 0.60 (0.05) | <.001 |
| GLS (%) | −18.30 (2.88) | −20.37 (2.24) | <.001 |
| Vascular studies | |||
| Pulse wave velocity (m/s) | 6.89 (1.70) | 7.24 (4.04) | .300 |
| Large artery elasticity (mL/mm Hg) | 17.44 (6.03) | 18.23 (5.01) | .060 |
| SAE (mL/mm Hg) | 6.94 (3.39) | 8.25 (3.43) | <.001 |
| Systolic blood pressure (mm Hg) | 124.75 (15.94) | 126.02 (12.51) | .410 |
| Diastolic blood pressure (mm Hg) | 74.34 (10.55) | 76.23 (9.87) | .078 |
P value from a linear regression model adjusted for age and sex.
DLCOcor, diffusion capacity of the lungs for carbon monoxide corrected for hemoglobin; FVC, forced vital capacity; TLC, total lung capacity.