Table 1. Characteristics of the main... | American Society of Hematology

Table 1.

Characteristics of the main histiocytoses subtypes

	LCH	ECD			RDD	Other histiocytoses	Total	Significance∗
	LCH	Pure	Mixed RDD	All	RDD	Other histiocytoses	Total	Significance∗
Number of patients	119†	53	15	72‡	70†	24§	284
Median age (y)	17.9	64	56.3	62.4	50.0	57.3	41.05	P < 10^-16 (Kruskall-Wallis rank sum test)
Sex (M/F; % of males)	77/42,;64.7%	46/7; 86.7%	11/4;73.3%	60/11; 84.5%	34/36; 48.6%	11/13; 45.8%	182/102; 64.1%	P < 10^-4 (χ² test)
Type of mutation (DELINs/SBSs, %DELINs)	109/10, 91.6%	10/43, 18.9%	3/12, 20%	15/56, 21.1%	3/67, 4.3%	6/18, 25.0%	133/151, 46.8%	P < 10^-16 (Fisher exact test)

	LCH	ECD			RDD	Other histiocytoses	Total	Significance∗
	LCH	Pure	Mixed RDD	All	RDD	Other histiocytoses	Total	Significance∗
Number of patients	119†	53	15	72‡	70†	24§	284
Median age (y)	17.9	64	56.3	62.4	50.0	57.3	41.05	P < 10^-16 (Kruskall-Wallis rank sum test)
Sex (M/F; % of males)	77/42,;64.7%	46/7; 86.7%	11/4;73.3%	60/11; 84.5%	34/36; 48.6%	11/13; 45.8%	182/102; 64.1%	P < 10^-4 (χ² test)
Type of mutation (DELINs/SBSs, %DELINs)	109/10, 91.6%	10/43, 18.9%	3/12, 20%	15/56, 21.1%	3/67, 4.3%	6/18, 25.0%	133/151, 46.8%	P < 10^-16 (Fisher exact test)

Comparing the 3 main groups LCH, all ECD, and RDD.

The 2 cases of mixed LCH-RDD are excluded from LCH and RDD and counted within “other histiocytoses.”

3 cases of ECD are mixed ECD-LCH.

12 malignant histiocytoses.