Changes in levels of FVIII, antithrombin, protein C, and protein S among those who stopped using CHCs and among controls
| . | Women who stopped CHC use (n = 66) . | Controls (n = 28) . | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FVIII (%) . | Antithrombin (%) . | Protein C (%) . | Protein S (%) . | FVIII (%) . | Antithrombin (%) . | Protein C (%) . | Protein S (%) . | |||||||||
| n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | |
| Baseline | 64 | 109 (27.1) | 65 | 91.6 (8.1) | 64 | 111.5 (23.3) | 57 | 85.3 (14.3) | 27 | 108.8 (27.6) | 28 | 95.5 (7.8) | 28 | 98.5 (18.7) | 28 | 83.7 (11.1) |
| 1 wk | 63 | 97.6 (28.2) | 64 | 95.4 (8.5) | 64 | 112.1 (23.7) | 58 | 84.9 (12.7) | — | — | — | — | — | — | — | — |
| 2 wk | 64 | 97.8 (29.9) | 63 | 94.7 (8.9) | 64 | 107.2 (23.7) | 57 | 86.7 (12.7) | — | — | — | — | — | — | — | — |
| 4 wk | 62 | 99.6 (27.7) | 61 | 92.4 (9.8) | 62 | 102.8 (22.5) | 55 | 89.2 (11.7) | 28 | 115.5 (32.2) | 28 | 94.7 (9.6) | 28 | 98.4 (21.1) | 28 | 84 (10.2) |
| 6 wk | 59 | 96.3 (24.8) | 59 | 90.9 (8.7) | 59 | 102.7 (20.6) | 54 | 87.5 (11.9) | — | — | — | — | — | — | — | — |
| 12 wk | 64 | 97.6 (25.1) | 65 | 92.4 (9.6) | 64 | 101.6 (22.7) | 59 | 90.4 (13.3) | 28 | 108.2 (28.3) | 28 | 94.7 (7.3) | 28 | 97.4 (16.9) | 28 | 81.9 (9) |
| . | Women who stopped CHC use (n = 66) . | Controls (n = 28) . | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FVIII (%) . | Antithrombin (%) . | Protein C (%) . | Protein S (%) . | FVIII (%) . | Antithrombin (%) . | Protein C (%) . | Protein S (%) . | |||||||||
| n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | n . | Mean (SD) . | |
| Baseline | 64 | 109 (27.1) | 65 | 91.6 (8.1) | 64 | 111.5 (23.3) | 57 | 85.3 (14.3) | 27 | 108.8 (27.6) | 28 | 95.5 (7.8) | 28 | 98.5 (18.7) | 28 | 83.7 (11.1) |
| 1 wk | 63 | 97.6 (28.2) | 64 | 95.4 (8.5) | 64 | 112.1 (23.7) | 58 | 84.9 (12.7) | — | — | — | — | — | — | — | — |
| 2 wk | 64 | 97.8 (29.9) | 63 | 94.7 (8.9) | 64 | 107.2 (23.7) | 57 | 86.7 (12.7) | — | — | — | — | — | — | — | — |
| 4 wk | 62 | 99.6 (27.7) | 61 | 92.4 (9.8) | 62 | 102.8 (22.5) | 55 | 89.2 (11.7) | 28 | 115.5 (32.2) | 28 | 94.7 (9.6) | 28 | 98.4 (21.1) | 28 | 84 (10.2) |
| 6 wk | 59 | 96.3 (24.8) | 59 | 90.9 (8.7) | 59 | 102.7 (20.6) | 54 | 87.5 (11.9) | — | — | — | — | — | — | — | — |
| 12 wk | 64 | 97.6 (25.1) | 65 | 92.4 (9.6) | 64 | 101.6 (22.7) | 59 | 90.4 (13.3) | 28 | 108.2 (28.3) | 28 | 94.7 (7.3) | 28 | 97.4 (16.9) | 28 | 81.9 (9) |