Baseline demographics and laboratory variables of all patients with iTTP and fatal outcomes
| Variable . | Number of patients, N (%), median (interquartile range; n = 33) . |
|---|---|
| Demographic | |
| Age (y) | 51 (28-60) |
| Sex | Female: 18 (54.5) Male: 15 (45.5) |
| Race | White/Caucasian: 13 (39.4) Black: 18 (54.5) |
| Presenting symptoms | |
| Any neurologic symptom | 22 (66.7) |
| Confusion | 10 (30.3) |
| Cerebrovascular accident | 9 (27.3) |
| Seizure | 3 (9.1) |
| Memory deficit | 1 (3) |
| Stupor/coma | 4 (12.1) |
| Headache | 7 (21.2) |
| Fever | 9 (27.3) |
| Chest pain | 0 (0) |
| Abdominal pain | 11 (33.3) |
| Fatigue | 11 (33.3) |
| Petechiae or easy bruising | 6 (18.2) |
| Dark urine | 4 (12.1) |
| Presence of any symptoms | 32 (97) |
| Presenting laboratory findings | |
| Platelet count (×103/μL) | 16.0 (10.2-19.8) |
| Lactate dehydrogenase (U/L) | 1574.5 (1260.5-2373.8) |
| Serum creatinine (mg/dL) | 1.6 (1.2-2.5) |
| Hemoglobin (g/dL) | 9.4 (7.8-10.5) |
| Peak troponin (ng/mL) | 0.9 (0.3-3.4) |
| ADAMTS13 confirmation available (yes/no) | 23 (69.7) |
| Variable . | Number of patients, N (%), median (interquartile range; n = 33) . |
|---|---|
| Demographic | |
| Age (y) | 51 (28-60) |
| Sex | Female: 18 (54.5) Male: 15 (45.5) |
| Race | White/Caucasian: 13 (39.4) Black: 18 (54.5) |
| Presenting symptoms | |
| Any neurologic symptom | 22 (66.7) |
| Confusion | 10 (30.3) |
| Cerebrovascular accident | 9 (27.3) |
| Seizure | 3 (9.1) |
| Memory deficit | 1 (3) |
| Stupor/coma | 4 (12.1) |
| Headache | 7 (21.2) |
| Fever | 9 (27.3) |
| Chest pain | 0 (0) |
| Abdominal pain | 11 (33.3) |
| Fatigue | 11 (33.3) |
| Petechiae or easy bruising | 6 (18.2) |
| Dark urine | 4 (12.1) |
| Presence of any symptoms | 32 (97) |
| Presenting laboratory findings | |
| Platelet count (×103/μL) | 16.0 (10.2-19.8) |
| Lactate dehydrogenase (U/L) | 1574.5 (1260.5-2373.8) |
| Serum creatinine (mg/dL) | 1.6 (1.2-2.5) |
| Hemoglobin (g/dL) | 9.4 (7.8-10.5) |
| Peak troponin (ng/mL) | 0.9 (0.3-3.4) |
| ADAMTS13 confirmation available (yes/no) | 23 (69.7) |