Table 1. Reactive peptides in alloSCT... | American Society of Hematology

Table 1.

Reactive peptides in alloSCT recipients

Name	Presenting HLA allele	ORF area	Epitope	Gene	Gene function (organism: human betaherpesvirus 5)
Pep01	A0301	Cryptic	RSALGPFVGK∗	UL36	Viral inhibitor of caspase-8-induced apoptosis
Pep02	A0301	Canonical	KLGYRPHAK∗	US33A	Uncharacterized protein US33A
Pep03	A0301	Canonical	GLYTQPRWK∗	UL77	CVC2 (Capsid vertex component 2)
Pep11	A0301	Cryptic	QLSRTHLSR	N/A
Pep12	B1501	Canonical	RQYDPVAAL†,‡	UL83	65 kDa phosphoprotein
Pep13	B1501	Canonical	ALKENTTVTF	*UL44*	DNA polymerase processivity factor
Pep15	B1501	Canonical	SQNYDYALY	*UL25*	Phosphoprotein 85
Pep17	B1501	Canonical	VLYQHRLVY	*UL57, DBP*	Major DNA-binding protein
Pep18	B1501	Canonical	YQRPMVQY	*UL36*	Viral inhibitor of caspase-8-induced apoptosis, vICA
Pep19	B1501	Cryptic	RIKTPGTVM	N/A

Name	Presenting HLA allele	ORF area	Epitope	Gene	Gene function (organism: human betaherpesvirus 5)
Pep01	A0301	Cryptic	RSALGPFVGK∗	UL36	Viral inhibitor of caspase-8-induced apoptosis
Pep02	A0301	Canonical	KLGYRPHAK∗	US33A	Uncharacterized protein US33A
Pep03	A0301	Canonical	GLYTQPRWK∗	UL77	CVC2 (Capsid vertex component 2)
Pep11	A0301	Cryptic	QLSRTHLSR	N/A
Pep12	B1501	Canonical	RQYDPVAAL†,‡	UL83	65 kDa phosphoprotein
Pep13	B1501	Canonical	ALKENTTVTF	*UL44*	DNA polymerase processivity factor
Pep15	B1501	Canonical	SQNYDYALY	*UL25*	Phosphoprotein 85
Pep17	B1501	Canonical	VLYQHRLVY	*UL57, DBP*	Major DNA-binding protein
Pep18	B1501	Canonical	YQRPMVQY	*UL36*	Viral inhibitor of caspase-8-induced apoptosis, vICA
Pep19	B1501	Cryptic	RIKTPGTVM	N/A

Characteristics of reactive peptides in PBMCs from allo-SCT recipients. Peptides were identified using UniProt.org.

Boldface indicates novel immunogenic peptides that were not found in the Immune Epitope Database.

N/A, not applicable; Pep, peptide; UL, long unique sequence; US, short unique sequence.

Previously published in Lübke et al.¹³

Previously published in Materne et al.³²

Previously published in Provenzano et al.³³