Table 1. Baseline characteristics of... | American Society of Hematology

Table 1.

Baseline characteristics of patients who received axi-cel in the mITT cohort

Covariate	Before PS matching				After PS matching
Covariate	Level	No BT, N = 132 (%)	BT, N = 143 (%)	P value	No BT, N = 97 (%)	BT, N = 97 (%)	P value
Age	≥65 y	32	31	.85	35	29	.37
Sex	Female	38	32	.26	30	33	.64
ECOG score	2-4	7	24	<.001	9	12	.49
Stage III or IV	Yes	74	88	.004	87	84	.68
IPI	3-5	36	66	<.001	48	54	.47
Prior lines of therapy	≥3	70	75	.34	70	68	.76
Refractory disease	Yes	72	78	.28	71	75	.51
Bulky disease	Yes	13	29	.001	17	21	.58
Prior auto-SCT	Yes	37	28	.1	32	32	>.99
Met ZUMA-1 eligibility	Yes	70	51	.002	64	61	.66
Double or triple hit	Yes	17	23	.16	19	24	.5
Cell or origin	Non-GCB	47	45	.77	44	46	.9
LDH at conditioning	<200	27	13	.01	22	17	.96
	200-300	21	24		26	26
	300-500	23	27		25	26
	≥500	24	32		24	27

Covariate	Before PS matching				After PS matching
Covariate	Level	No BT, N = 132 (%)	BT, N = 143 (%)	P value	No BT, N = 97 (%)	BT, N = 97 (%)	P value
Age	≥65 y	32	31	.85	35	29	.37
Sex	Female	38	32	.26	30	33	.64
ECOG score	2-4	7	24	<.001	9	12	.49
Stage III or IV	Yes	74	88	.004	87	84	.68
IPI	3-5	36	66	<.001	48	54	.47
Prior lines of therapy	≥3	70	75	.34	70	68	.76
Refractory disease	Yes	72	78	.28	71	75	.51
Bulky disease	Yes	13	29	.001	17	21	.58
Prior auto-SCT	Yes	37	28	.1	32	32	>.99
Met ZUMA-1 eligibility	Yes	70	51	.002	64	61	.66
Double or triple hit	Yes	17	23	.16	19	24	.5
Cell or origin	Non-GCB	47	45	.77	44	46	.9
LDH at conditioning	<200	27	13	.01	22	17	.96
	200-300	21	24		26	26
	300-500	23	27		25	26
	≥500	24	32		24	27

Auto-SCT, autologous stem cell transplant; non-GCB, germinal center B cell.