Table 3.

GVHD characteristics and patient response to steroid treatment

Patient response to steroids
Plus single-agent PPXNo PPX
Number of patients, N 12 12 
aGVHD   
Grade 1, n (%) 1 (8) 2 (17) 
Grade 2-4, n (%) 1 (8) 7 (58) 
D to diagnosis, median (range) 61 (24-97) 41 (13-86) 
aGVHD treatment   
Systemic corticosteroids, n (%) — 1 (11) 
Systemic corticosteroids and other, n (%) 1 (50) 6 (67) 
Other therapies, n (%) 1 (50) 1 (11) 
Complete resolution of aGVHD, n (%) 2 (100) 9 (100) 
cGVHD   
Mild, n (%) 1 (8) 2 (17) 
Moderate to severe, n (%) — 3 (25) 
cGVHD treatment   
Systemic corticosteroids and CNI, n (%) — 2 (40) 
Systemic corticosteroids, CNI, and other, n (%) — 3 (60) 
Other therapies, n (%) 1 (100) — 
Complete resolution of cGVHD, n (%) 1 (100) 5 (100) 
Patient response to steroids
Plus single-agent PPXNo PPX
Number of patients, N 12 12 
aGVHD   
Grade 1, n (%) 1 (8) 2 (17) 
Grade 2-4, n (%) 1 (8) 7 (58) 
D to diagnosis, median (range) 61 (24-97) 41 (13-86) 
aGVHD treatment   
Systemic corticosteroids, n (%) — 1 (11) 
Systemic corticosteroids and other, n (%) 1 (50) 6 (67) 
Other therapies, n (%) 1 (50) 1 (11) 
Complete resolution of aGVHD, n (%) 2 (100) 9 (100) 
cGVHD   
Mild, n (%) 1 (8) 2 (17) 
Moderate to severe, n (%) — 3 (25) 
cGVHD treatment   
Systemic corticosteroids and CNI, n (%) — 2 (40) 
Systemic corticosteroids, CNI, and other, n (%) — 3 (60) 
Other therapies, n (%) 1 (100) — 
Complete resolution of cGVHD, n (%) 1 (100) 5 (100) 

aGVHD, acute graft-versus-host disease; cGVHD, chronic GVHD

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