Diagnostic criteria
| Normal physical examination |
| No history of congenital thrombocytopenia |
| No alterations at the blood smear apart from thrombocytopenia |
| Bone marrow aspirate morphology: compatible with isolated thrombocytopenia |
| Absence of autoimmunity markers (anti-nucleus, anti-thyroglobulin, and anti-thyroid peroxidase antibodies; anti-cardiolipin and anti–β2-glycoprotein antibodies; and Lupus anticoagulant) and direct anti-globulin test |
| Normal coagulation parameters |
| Normal serum biochemistry: glucose, urea, creatinine, uric acid, bilirubin, AST, ALT, alkaline phosphatase, LDH, sodium, potassium, calcium, total proteins and electrophoresis, and albumin |
| Absence of lymphadenopathies; liver and spleen enlargement |
| Absence of neoplasms |
| Absence of acute or chronic infectious diseases |
| Normal physical examination |
| No history of congenital thrombocytopenia |
| No alterations at the blood smear apart from thrombocytopenia |
| Bone marrow aspirate morphology: compatible with isolated thrombocytopenia |
| Absence of autoimmunity markers (anti-nucleus, anti-thyroglobulin, and anti-thyroid peroxidase antibodies; anti-cardiolipin and anti–β2-glycoprotein antibodies; and Lupus anticoagulant) and direct anti-globulin test |
| Normal coagulation parameters |
| Normal serum biochemistry: glucose, urea, creatinine, uric acid, bilirubin, AST, ALT, alkaline phosphatase, LDH, sodium, potassium, calcium, total proteins and electrophoresis, and albumin |
| Absence of lymphadenopathies; liver and spleen enlargement |
| Absence of neoplasms |
| Absence of acute or chronic infectious diseases |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase.