Adverse drug reactions
| . | Grade . | Arm . | ||
|---|---|---|---|---|
| A . | B . | Total events . | ||
| Retinal toxicity | 3 | 1 | 0 | 1 |
| Edemas | 1 | 0 | 1 | 1 |
| 2 | 3 | 0 | 3 | |
| Insomnia | 2 | 4 | 1 | 5 |
| 3 | 1 | 0 | 1 | |
| Hypertension | 3 | 1 | 0 | 1 |
| Weight gain | 2 | 5 | 0 | 5 |
| 3 | 2 | 0 | 2 | |
| Fluid retention | - | 1 | 0 | 1 |
| Cushing's syndrome | - | 1 | 0 | 1 |
| . | Grade . | Arm . | ||
|---|---|---|---|---|
| A . | B . | Total events . | ||
| Retinal toxicity | 3 | 1 | 0 | 1 |
| Edemas | 1 | 0 | 1 | 1 |
| 2 | 3 | 0 | 3 | |
| Insomnia | 2 | 4 | 1 | 5 |
| 3 | 1 | 0 | 1 | |
| Hypertension | 3 | 1 | 0 | 1 |
| Weight gain | 2 | 5 | 0 | 5 |
| 3 | 2 | 0 | 2 | |
| Fluid retention | - | 1 | 0 | 1 |
| Cushing's syndrome | - | 1 | 0 | 1 |
Grading according to the National Cancer Institute: Common Toxicity Criteria Adverse Events, version 3.0.20