Minimal epitopes within the IDH2R140Qneoantigen and associated HLA restriction
| Mutant-specific epitope . | Position . | CD4 or CD8 response . | Responding donors . | HLA restriction . |
|---|---|---|---|---|
| TIQNILGGTV (10-TIQ) | AA 138-147 | CD8 | Donor 5 Donor 12 | B∗15:01 A∗02:06 |
| IQNILGGTVF (10-TIQ) | AA 139-148 | CD8 | Donor 7 Donor 20 | B∗35:43 B∗44:02 |
| SPNGTIQNILGGTVF (15-SPN) | AA 134-148 | CD4 | Donor 7 | DR∗08 |
| Mutant-specific epitope . | Position . | CD4 or CD8 response . | Responding donors . | HLA restriction . |
|---|---|---|---|---|
| TIQNILGGTV (10-TIQ) | AA 138-147 | CD8 | Donor 5 Donor 12 | B∗15:01 A∗02:06 |
| IQNILGGTVF (10-TIQ) | AA 139-148 | CD8 | Donor 7 Donor 20 | B∗35:43 B∗44:02 |
| SPNGTIQNILGGTVF (15-SPN) | AA 134-148 | CD4 | Donor 7 | DR∗08 |