Characteristics of the study population of patients with HAE and their relatives
| . | Participants, n (%) . | |||
|---|---|---|---|---|
| All (2006) . | HAE (n = 365) . | Non-HAE (n = 1641) . | P value . | |
| Sex | ||||
| Male | 1017 (50.70) | 152 (41.64) | 865 (52.71) | <.001∗ |
| Female | 989 (49.30) | 213 (58.36) | 776 (47.29) | |
| Birth year | ||||
| Mean (SD) (min-max) | 1964 (27) (1892-2018) | 1966 (22) (1914-2009) | 1963 (27) (1892-2018) | .022† |
| Median (Q1-Q3) | 1964 (1945-1984) | 1966 (1951-1984) | 1963 (1944-1984) | |
| Education | ||||
| Unknown or <10 y | 472 (23.53) | 61 (16.71) | 411 (25.05) | |
| 10-11 y | 834 (41.58) | 180 (49.32) | 654 (39.85) | <.001∗ |
| >11 y | 700 (34.90) | 124 (33.97) | 576 (35.10) | |
| Country of birth outside Sweden | 184 (9.17) | 45 (12.33) | 139 (8.47) | .021∗ |
| Age at HAE onset | ||||
| Mean (SD) (min-max) | NA | 40 (22) (0-94) | NA | |
| Median (Q1-Q3) | NA | 39 (24-56) | NA | |
| Age at end of follow-up | ||||
| Mean (SD) (min-max) | 49 (24) (0-101) | 40 (22) (0-94) | 51 (24) (0-101) | |
| Median (Q1-Q3) | 51 (31-68) | 39 (24-56) | 53 (33-70) | <.001† |
| VTE | 103 (5.13) | 35 (9.59) | 68 (4.14) | <.001∗ |
| . | Participants, n (%) . | |||
|---|---|---|---|---|
| All (2006) . | HAE (n = 365) . | Non-HAE (n = 1641) . | P value . | |
| Sex | ||||
| Male | 1017 (50.70) | 152 (41.64) | 865 (52.71) | <.001∗ |
| Female | 989 (49.30) | 213 (58.36) | 776 (47.29) | |
| Birth year | ||||
| Mean (SD) (min-max) | 1964 (27) (1892-2018) | 1966 (22) (1914-2009) | 1963 (27) (1892-2018) | .022† |
| Median (Q1-Q3) | 1964 (1945-1984) | 1966 (1951-1984) | 1963 (1944-1984) | |
| Education | ||||
| Unknown or <10 y | 472 (23.53) | 61 (16.71) | 411 (25.05) | |
| 10-11 y | 834 (41.58) | 180 (49.32) | 654 (39.85) | <.001∗ |
| >11 y | 700 (34.90) | 124 (33.97) | 576 (35.10) | |
| Country of birth outside Sweden | 184 (9.17) | 45 (12.33) | 139 (8.47) | .021∗ |
| Age at HAE onset | ||||
| Mean (SD) (min-max) | NA | 40 (22) (0-94) | NA | |
| Median (Q1-Q3) | NA | 39 (24-56) | NA | |
| Age at end of follow-up | ||||
| Mean (SD) (min-max) | 49 (24) (0-101) | 40 (22) (0-94) | 51 (24) (0-101) | |
| Median (Q1-Q3) | 51 (31-68) | 39 (24-56) | 53 (33-70) | <.001† |
| VTE | 103 (5.13) | 35 (9.59) | 68 (4.14) | <.001∗ |