Clinical characterization of human participants
| . | Non-CKD n = 17 . | CKD n = 18 . |
|---|---|---|
| Female, n | 10/7 | 9/9 |
| Age (y) | 40 (26-51) | 45 (33-52) |
| Hb (g/dL) | 9.3 (7.0-10.0) | 8.1 (6.6-9.4) |
| White blood cells (×103/μL) | 11.0 (8.7-12.5) | 10.2 (6.6-12.3) |
| Neutrophils (×103/μL) | 5.3 (4.9-6.1) | 5.8 (3.2-7.7) |
| Platelets (×103/μL) | 371 (354-501) | 323 (223-410) |
| HbS (%) | 78 (40-90) | 75 (59-88) |
| HbF (%) | 5 (1-9) | 7 (3-17) |
| SS genotype, n | 17 | 17 |
| Hydroxyurea, n | 4 | 10 |
| . | Non-CKD n = 17 . | CKD n = 18 . |
|---|---|---|
| Female, n | 10/7 | 9/9 |
| Age (y) | 40 (26-51) | 45 (33-52) |
| Hb (g/dL) | 9.3 (7.0-10.0) | 8.1 (6.6-9.4) |
| White blood cells (×103/μL) | 11.0 (8.7-12.5) | 10.2 (6.6-12.3) |
| Neutrophils (×103/μL) | 5.3 (4.9-6.1) | 5.8 (3.2-7.7) |
| Platelets (×103/μL) | 371 (354-501) | 323 (223-410) |
| HbS (%) | 78 (40-90) | 75 (59-88) |
| HbF (%) | 5 (1-9) | 7 (3-17) |
| SS genotype, n | 17 | 17 |
| Hydroxyurea, n | 4 | 10 |
Cells contain median (interquartile range [IQR]) unless otherwise specified.
HbF, hb F (fetal); HbS, hb S (sickle).