Assessment of IgG testing among patients diagnosed with CLL and NHL receiving 1 or more IgG testing during follow-up
| Characteristics . | CLL (n = 2652) . | NHL (n = 6773) . |
|---|---|---|
| Number of IgG testing per patient during the follow-up period | ||
| Mean ± SD | 6.3 ± 10.0 | 7.8 ± 13.2 |
| Median (IQR) | 2.0 (1.0-7.0) | 2.0 (1.0-8.0) |
| Number of IgG testing per patient during the follow-up period, n (%) | ||
| 1 | 909 (34.3) | 2467 (36.4) |
| 2 | 422 (15.9) | 1042 (15.4) |
| 3 | 269 (10.1) | 502 (7.4) |
| 4 | 163 (6.1) | 337 (5.0) |
| 5 | 120 (4.5) | 233 (3.4) |
| 6 | 88 (3.3) | 204 (3.0) |
| 7 | 83 (3.1) | 166 (2.5) |
| ≥8 | 598 (22.5) | 1822 (26.9) |
| Number of IgG testing per patient per year | ||
| Mean ± SD | 1.5 ± 4.2 | 2.5 ± 15.7 |
| Median (IQR) | 0.6 (0.3-1.4) | 0.7 (0.3-2.2) |
| Number of patients with IgG testing on the date of first diagnosis, n (%) | 768 (29.0) | 1127 (16.6) |
| Number of patients with IgG testing after the date of first diagnosis, n (%) | 1884 (71.0) | 5646 (83.4) |
| Time from diagnosis to first IgG testing, mo | ||
| Mean ± SD | 13.0 ± 21.6 | 12.8 ± 21.8 |
| Median (IQR) | 3.0 (0.6-14.8) | 2.8 (0.5-14.6) |
| Time from first IgG testing to end of follow-up, y | ||
| Mean ± SD | 4.9 ± 3.2 | 4.6 ± 3.3 |
| Median (IQR) | 4.5 (2.1-7.2) | 4.0 (1.8-6.8) |
| Proportion of patients with hypogammaglobulinemia, n (%) | ||
| Any IgG test level of <500 mg/dL | 917 (34.6) | 2411 (35.6) |
| First IgG test level of <500 mg/dL | 593 (22.4) | 1615 (23.8) |
| Lowest IgG test result (mg/dL)∗ , n (%) | ||
| <200 | 250 (9.4) | 627 (9.3) |
| ≥200 to <400 | 430 (16.2) | 1115 (16.5) |
| ≥400 to <500 | 237 (8.9) | 669 (9.9) |
| ≥500 to <600 | 317 (12.0) | 688 (10.2) |
| ≥600 | 1418 (53.5) | 3674 (54.2) |
| Characteristics . | CLL (n = 2652) . | NHL (n = 6773) . |
|---|---|---|
| Number of IgG testing per patient during the follow-up period | ||
| Mean ± SD | 6.3 ± 10.0 | 7.8 ± 13.2 |
| Median (IQR) | 2.0 (1.0-7.0) | 2.0 (1.0-8.0) |
| Number of IgG testing per patient during the follow-up period, n (%) | ||
| 1 | 909 (34.3) | 2467 (36.4) |
| 2 | 422 (15.9) | 1042 (15.4) |
| 3 | 269 (10.1) | 502 (7.4) |
| 4 | 163 (6.1) | 337 (5.0) |
| 5 | 120 (4.5) | 233 (3.4) |
| 6 | 88 (3.3) | 204 (3.0) |
| 7 | 83 (3.1) | 166 (2.5) |
| ≥8 | 598 (22.5) | 1822 (26.9) |
| Number of IgG testing per patient per year | ||
| Mean ± SD | 1.5 ± 4.2 | 2.5 ± 15.7 |
| Median (IQR) | 0.6 (0.3-1.4) | 0.7 (0.3-2.2) |
| Number of patients with IgG testing on the date of first diagnosis, n (%) | 768 (29.0) | 1127 (16.6) |
| Number of patients with IgG testing after the date of first diagnosis, n (%) | 1884 (71.0) | 5646 (83.4) |
| Time from diagnosis to first IgG testing, mo | ||
| Mean ± SD | 13.0 ± 21.6 | 12.8 ± 21.8 |
| Median (IQR) | 3.0 (0.6-14.8) | 2.8 (0.5-14.6) |
| Time from first IgG testing to end of follow-up, y | ||
| Mean ± SD | 4.9 ± 3.2 | 4.6 ± 3.3 |
| Median (IQR) | 4.5 (2.1-7.2) | 4.0 (1.8-6.8) |
| Proportion of patients with hypogammaglobulinemia, n (%) | ||
| Any IgG test level of <500 mg/dL | 917 (34.6) | 2411 (35.6) |
| First IgG test level of <500 mg/dL | 593 (22.4) | 1615 (23.8) |
| Lowest IgG test result (mg/dL)∗ , n (%) | ||
| <200 | 250 (9.4) | 627 (9.3) |
| ≥200 to <400 | 430 (16.2) | 1115 (16.5) |
| ≥400 to <500 | 237 (8.9) | 669 (9.9) |
| ≥500 to <600 | 317 (12.0) | 688 (10.2) |
| ≥600 | 1418 (53.5) | 3674 (54.2) |
SD, standard deviation.
For patients with multiple IgG tests, the lowest test result during the follow-up was used.