Study characteristics
| Data set . | Study . | Country . | No. of centers . | Data collection period . | UCD (n) . | iMCD (n) . | HHV8+ MCD (n) . |
|---|---|---|---|---|---|---|---|
| Aggregate | Alzahrani et al11 | Canada/Saudi Arabia | 2 | January 2005-September 2012 | 12 | ||
| Dong et al12 | China | 1 | November 1977-June 2014 | 62 | 52 | ||
| Lan et al13 | China | 1 | September 2011-September 2017 | 35 | 36 | ||
| Zhang et al14 | China | 4 | January 2001-January 2015 | 121 | 64 | ||
| Zhang et al15 ∗ | China | 1 | June 2015-June 2018 | 25 | |||
| Zhang et al16 | China | 1 | March 2008-June 2019 | 52 | 44 | ||
| Zhao et al17 | China | 1 | January 2010-May 2017 | 65 | 9 | ||
| Boutboul et al18 | France | National study | 1997-2017 | 71 | |||
| Oksenhendler et al3 | France | 1 | 1997-2017 | 27 | 169 | ||
| Hoffmann et al19 | Germany | 11 | January 1998-July 2010 | 52 | |||
| Prakash et al20 | India | 1 | 2002-2014 | 8 | 8 | ||
| Fujimoto et al21 | Japan | 77 | October 2013-October 2016 | 150 | |||
| Iwaki et al22 | Japan | 1 | 1999-2013 | 17 | |||
| Kawabata et al23 | Japan | 1 | January 2005-October 2012 | 21 | |||
| Murakami et al24 † | Japan | National study | June 2005-July 2011 | 342 | |||
| Nishimura et al25 | Japan | 1 | April 2012-June 2018 | 7 | |||
| Volkow-Fernández et al (2020)26 | Mexico | 1 | January 1994-December 2018 | 19 | |||
| Melikyan et al27 | Russia | 1 | 1996-2016 | 6 | |||
| Seo et al28 | South Korea | 1 | January 1990-March 2013 | 28 | |||
| Shin et al29 | South Korea | 1 | May 1981-March 2009 | 43 | 27 | ||
| Gonzalez-Garcia et al30 | Spain | 1 | January 1985-December 2017 | 20 | 23 | ||
| Bower et al31 | United Kingdom | 1 | 2000-2014 | 75 | |||
| Casper et al32 | United States | 2 | 1 January 2000 to 31 December 2009 | 53 | 6 | ||
| Chronowski et al33 | United States | 1 | 1988-1999 | 12 | 9 | ||
| Dispenzieri et al34 | United States | 2 | 30 March 1948 to 18 June 2002 | 53 | 60 | ||
| Herrada et al35 | United States | 1 | March 1977-October 1995 | 8 | |||
| Hill et al36 | United States | 1 | 1997-2012 | 17 | 13 | ||
| Lurain et al37 | United States | National study | 2000-2013 | 19 | |||
| Ramaswami et al38 ‡ | United States | National study | 2011-2018 | 8 | |||
| Uldrick et al39 § | United States | National study | 2004-2009 | 14 | |||
| Uldrick et al40 ‖ | United States | National study | March 2006-September 2010 | 17 | |||
| Venkataraman et al41 | United States | National study | 2004-2010 | 19 | |||
| Pediatric | Parez et al42 | Canada/France | 2 | Not reported | 7 | ||
| Zhang et al43 | China | 1 | January 2001-December 2012 | 9 | 2 | ||
| Borocco et al44 | France | 3 societies | 2016 | 17 | 6 | ||
| Chisholm et al45 | United States | 2 | 1980-2018 | 37 | 2 | ||
| Sopfe et al46 | United States | 1 | 1 January 2005 to 16 May 2017 | 18 | 6 | ||
| Patient-level | Loi et al47 | Australia | 3 | January 1994-December 2001 | 11 | ||
| Dong et al48 | China | 1 | November 1977-July 2008 | 34 | 21 | ||
| Wang et al49 | China | 1 | September 2007-October 2015 | 14 | |||
| Ye et al50 | China | 1 | January 1999-November 2008 | 48 | 4 | ||
| Zhu et al51 | China | 1 | May 2004-October 2012 | 10 | |||
| Dossier et al52 | France | 1 | January 1995-June 2012 | 12 | 18 | ||
| Oksenhendler et al53 ¶ | France/United Kingdom | 1 | 1990-2001 | 60 | |||
| Kojima et al54 | Japan | Not reported | 1992-2007 | 28 | |||
| Sato et al55 | Japan | 1 | Not reported | 6 | |||
| Terasaki et al56 | Japan | 1 | Not reported | 15 | |||
| Gopal et al (2015)57 # | Malawi | 1 | 1 June 2013 to 31 January 2015 | 6 | |||
| Ghosh et al58 | Nepal | 1 | January 2001-March 2008 | 5 | |||
| Kim et al59 | South Korea | 1 | 1989-1998 | 10 | 12 | ||
| Lachmann et al60 | United Kingdom | 1 | Not reported | 5 | |||
| Bowne et al61 | United States | 1 | July 1986-July 1997 | 13 | 3 |
| Data set . | Study . | Country . | No. of centers . | Data collection period . | UCD (n) . | iMCD (n) . | HHV8+ MCD (n) . |
|---|---|---|---|---|---|---|---|
| Aggregate | Alzahrani et al11 | Canada/Saudi Arabia | 2 | January 2005-September 2012 | 12 | ||
| Dong et al12 | China | 1 | November 1977-June 2014 | 62 | 52 | ||
| Lan et al13 | China | 1 | September 2011-September 2017 | 35 | 36 | ||
| Zhang et al14 | China | 4 | January 2001-January 2015 | 121 | 64 | ||
| Zhang et al15 ∗ | China | 1 | June 2015-June 2018 | 25 | |||
| Zhang et al16 | China | 1 | March 2008-June 2019 | 52 | 44 | ||
| Zhao et al17 | China | 1 | January 2010-May 2017 | 65 | 9 | ||
| Boutboul et al18 | France | National study | 1997-2017 | 71 | |||
| Oksenhendler et al3 | France | 1 | 1997-2017 | 27 | 169 | ||
| Hoffmann et al19 | Germany | 11 | January 1998-July 2010 | 52 | |||
| Prakash et al20 | India | 1 | 2002-2014 | 8 | 8 | ||
| Fujimoto et al21 | Japan | 77 | October 2013-October 2016 | 150 | |||
| Iwaki et al22 | Japan | 1 | 1999-2013 | 17 | |||
| Kawabata et al23 | Japan | 1 | January 2005-October 2012 | 21 | |||
| Murakami et al24 † | Japan | National study | June 2005-July 2011 | 342 | |||
| Nishimura et al25 | Japan | 1 | April 2012-June 2018 | 7 | |||
| Volkow-Fernández et al (2020)26 | Mexico | 1 | January 1994-December 2018 | 19 | |||
| Melikyan et al27 | Russia | 1 | 1996-2016 | 6 | |||
| Seo et al28 | South Korea | 1 | January 1990-March 2013 | 28 | |||
| Shin et al29 | South Korea | 1 | May 1981-March 2009 | 43 | 27 | ||
| Gonzalez-Garcia et al30 | Spain | 1 | January 1985-December 2017 | 20 | 23 | ||
| Bower et al31 | United Kingdom | 1 | 2000-2014 | 75 | |||
| Casper et al32 | United States | 2 | 1 January 2000 to 31 December 2009 | 53 | 6 | ||
| Chronowski et al33 | United States | 1 | 1988-1999 | 12 | 9 | ||
| Dispenzieri et al34 | United States | 2 | 30 March 1948 to 18 June 2002 | 53 | 60 | ||
| Herrada et al35 | United States | 1 | March 1977-October 1995 | 8 | |||
| Hill et al36 | United States | 1 | 1997-2012 | 17 | 13 | ||
| Lurain et al37 | United States | National study | 2000-2013 | 19 | |||
| Ramaswami et al38 ‡ | United States | National study | 2011-2018 | 8 | |||
| Uldrick et al39 § | United States | National study | 2004-2009 | 14 | |||
| Uldrick et al40 ‖ | United States | National study | March 2006-September 2010 | 17 | |||
| Venkataraman et al41 | United States | National study | 2004-2010 | 19 | |||
| Pediatric | Parez et al42 | Canada/France | 2 | Not reported | 7 | ||
| Zhang et al43 | China | 1 | January 2001-December 2012 | 9 | 2 | ||
| Borocco et al44 | France | 3 societies | 2016 | 17 | 6 | ||
| Chisholm et al45 | United States | 2 | 1980-2018 | 37 | 2 | ||
| Sopfe et al46 | United States | 1 | 1 January 2005 to 16 May 2017 | 18 | 6 | ||
| Patient-level | Loi et al47 | Australia | 3 | January 1994-December 2001 | 11 | ||
| Dong et al48 | China | 1 | November 1977-July 2008 | 34 | 21 | ||
| Wang et al49 | China | 1 | September 2007-October 2015 | 14 | |||
| Ye et al50 | China | 1 | January 1999-November 2008 | 48 | 4 | ||
| Zhu et al51 | China | 1 | May 2004-October 2012 | 10 | |||
| Dossier et al52 | France | 1 | January 1995-June 2012 | 12 | 18 | ||
| Oksenhendler et al53 ¶ | France/United Kingdom | 1 | 1990-2001 | 60 | |||
| Kojima et al54 | Japan | Not reported | 1992-2007 | 28 | |||
| Sato et al55 | Japan | 1 | Not reported | 6 | |||
| Terasaki et al56 | Japan | 1 | Not reported | 15 | |||
| Gopal et al (2015)57 # | Malawi | 1 | 1 June 2013 to 31 January 2015 | 6 | |||
| Ghosh et al58 | Nepal | 1 | January 2001-March 2008 | 5 | |||
| Kim et al59 | South Korea | 1 | 1989-1998 | 10 | 12 | ||
| Lachmann et al60 | United Kingdom | 1 | Not reported | 5 | |||
| Bowne et al61 | United States | 1 | July 1986-July 1997 | 13 | 3 |
Most publications described retrospective studies, except for 7 prospective studies marked by respective footnote symbols in the table.
Single-center, single-arm, phase 2 study
Prospective observational study
Open-label, single-center pilot study
Prospective pilot study
Prospective study
Prospective cohort study
Prospective longitudinal cohort study