Patient summary
UPN . | Dose level (mCi/kg) . | Age at AHCT, y . | Prior lines . | Diagnosis . | Prior therapies . | Disease status at AHCT . | Response after AHCT, day 100 . | Current status . |
---|---|---|---|---|---|---|---|---|
1 | 0.4 | 50 | 1 | PTCL-NOS | R-EPOCH ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
2 | 0.4 | 45 | 1 | PTCL-NOS | R-EPOCH ×6 | CR1 | CR | Relapsed at day +301, died of PTCL ∼17 mos after AHCT |
4 | 0.4 | 50 | 1 | AITL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼1.5 y after AHCT |
5 | 0.4 | 71 | 1 | PTCL-NOS | CHOP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
6 | 0.5 | 48 | 1 | HSTCL | EPOCH + BV ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
7 | 0.5 | 74 | 1 | MEITL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
9 | 0.5 | 76 | 1 | PTCL-NOS | CHOEP ×6 | CR1 | CR | Relapsed at day +218, died of PTCL ∼11 mos after AHCT |
10 | 0.5 | 18 | 1 | PTCL-NOS | CHOEP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
11 | 0.6 | 41 | 2 | PTCL-NOS | CHOP ×6 | CR1 | CR | Relapsed at day +514, still alive ∼2 y after AHCT |
12 | 0.6 | 51 | 1 | ALK-ve ALCL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼1 y after AHCT |
13 | 0.6 | 60 | 1 | AITL | CHOEP ×6 | CR1 | Relapse | Relapsed at day +108, died of PTCL ∼21 mos after AHCT |
14 | 0.6 | 52 | 1 | ALK-ve ALCL | CHOP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
15 | 0.6 | 44 | 2 | ALK-ve ALCL | ABVD – BV ×6 (CR1) | CR2 | Relapse | Relapsed at day +105, died of PTCL ∼9 mos after AHCT |
16 | 0.6 | 76 | 2 | MEITL | Newcastle regimen (CR1) Gem/Ox – CR2 | CR2 | Relapse | Relapsed at day +118, died of PTCL ∼18 mos after AHCT |
17 | 0.6 | 54 | 1 | AITL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
18 | 0.6 | 62 | 1 | PTCL-NOS | CHOP ×6 | CR1 | CR | Relapsed at day +269, died of multiorgan failure ∼9 mos after AHCT |
19 | 0.6 | 62 | 1 | PTCL-NOS | CHOP ×6 | CR1 | CR | Relapsed at day +360, still alive ∼2 y after AHCT |
20 | 0.6 | 63 | 4 | PTCL-NOS CD30+ | Cytoxan ×1, etoposide ×1, romidepsin ×3 infusions, BV ×6 – CR1 | CR1 | CR | Alive without relapse ∼1.5 y after AHCT |
21 | 0.6 | 46 | 2 | ALK-ve ALCL | CHOEP ×3 – BV ×8 – CR1 | CR1 | CR | Alive without relapse ∼1.5 y after AHCT |
22 | 0.6 | 32 | 1 | ALK-ve ALCL | A + CHP ×6 | CR1 | CR | Alive without relapse ∼7 mos after AHCT |
UPN . | Dose level (mCi/kg) . | Age at AHCT, y . | Prior lines . | Diagnosis . | Prior therapies . | Disease status at AHCT . | Response after AHCT, day 100 . | Current status . |
---|---|---|---|---|---|---|---|---|
1 | 0.4 | 50 | 1 | PTCL-NOS | R-EPOCH ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
2 | 0.4 | 45 | 1 | PTCL-NOS | R-EPOCH ×6 | CR1 | CR | Relapsed at day +301, died of PTCL ∼17 mos after AHCT |
4 | 0.4 | 50 | 1 | AITL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼1.5 y after AHCT |
5 | 0.4 | 71 | 1 | PTCL-NOS | CHOP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
6 | 0.5 | 48 | 1 | HSTCL | EPOCH + BV ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
7 | 0.5 | 74 | 1 | MEITL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
9 | 0.5 | 76 | 1 | PTCL-NOS | CHOEP ×6 | CR1 | CR | Relapsed at day +218, died of PTCL ∼11 mos after AHCT |
10 | 0.5 | 18 | 1 | PTCL-NOS | CHOEP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
11 | 0.6 | 41 | 2 | PTCL-NOS | CHOP ×6 | CR1 | CR | Relapsed at day +514, still alive ∼2 y after AHCT |
12 | 0.6 | 51 | 1 | ALK-ve ALCL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼1 y after AHCT |
13 | 0.6 | 60 | 1 | AITL | CHOEP ×6 | CR1 | Relapse | Relapsed at day +108, died of PTCL ∼21 mos after AHCT |
14 | 0.6 | 52 | 1 | ALK-ve ALCL | CHOP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
15 | 0.6 | 44 | 2 | ALK-ve ALCL | ABVD – BV ×6 (CR1) | CR2 | Relapse | Relapsed at day +105, died of PTCL ∼9 mos after AHCT |
16 | 0.6 | 76 | 2 | MEITL | Newcastle regimen (CR1) Gem/Ox – CR2 | CR2 | Relapse | Relapsed at day +118, died of PTCL ∼18 mos after AHCT |
17 | 0.6 | 54 | 1 | AITL | CHOEP ×6 | CR1 | CR | Alive without relapse ∼2 y after AHCT |
18 | 0.6 | 62 | 1 | PTCL-NOS | CHOP ×6 | CR1 | CR | Relapsed at day +269, died of multiorgan failure ∼9 mos after AHCT |
19 | 0.6 | 62 | 1 | PTCL-NOS | CHOP ×6 | CR1 | CR | Relapsed at day +360, still alive ∼2 y after AHCT |
20 | 0.6 | 63 | 4 | PTCL-NOS CD30+ | Cytoxan ×1, etoposide ×1, romidepsin ×3 infusions, BV ×6 – CR1 | CR1 | CR | Alive without relapse ∼1.5 y after AHCT |
21 | 0.6 | 46 | 2 | ALK-ve ALCL | CHOEP ×3 – BV ×8 – CR1 | CR1 | CR | Alive without relapse ∼1.5 y after AHCT |
22 | 0.6 | 32 | 1 | ALK-ve ALCL | A + CHP ×6 | CR1 | CR | Alive without relapse ∼7 mos after AHCT |
Alk-ve ALCL, Anaplastic large cell lymphoma; Gem/Ox, gemcitabine and oxaliplatin; HSTCL, hepatosplenic T-cell lymphoma; MEITL, monomorphic epithelial intestinal T-cell lymphoma; UPN- unidentified patient number.