Studies measuring TF antigen in plasma using IMUBIND and Quantikine ELISAs
| Disease . | Kit . | Healthy group TF antigen (pg/mL) . | Disease group TF antigen (pg/mL) . | Data type . | P value . | Reference . |
|---|---|---|---|---|---|---|
| Leukemia | IMUBIND | 117 ± 19.2 | 273 ± 90 | Mean ± SD | <.01 | 44 |
| Coronary artery disease | IMUBIND | 187.3 ± 108.7 | 303.6 ± 134.1 | Mean ± SD | <.05 | 45 |
| Peripheral artery disease | IMUBIND | 158 ± 60 | 275 ± 122 | Mean ± SD | <.0001 | 46 |
| Ischemic heart disease | IMUBIND | 142 (18-262) | 179.2 (51.2-380) (stable) 215 (56.8-834.3) (unstable) | Median (IQR) | <.0001 <.0001 | 47 |
| Coronary artery disease | IMUBIND | 76 (32-108) | 116 (92-150) (stable) | Median (IQR) | <.01 | 48 |
| 146 (104-188) (unstable) | <.001 | |||||
| Glomerulonephritis | IMUBIND | 144 ± 73.9 | 283 ± 145 | Mean ± SD | .009 | 49 |
| Non–small cell lung cancer | IMUBIND | 124.1 ± 14.79 | 334.9 ± 95.44 | Mean ± SD | .02 | 50 |
| Obstructive sleep apnea | IMUBIND | 42.83 ± 14.18 | 66.78 ± 41.59 | Mean ± SD | .005 | 51 |
| Aneurysm | IMUBIND | 62 ± 20 | 134 ± 54 (AAA) | Mean ± SD | <.001 | 52 |
| 91 ± 30 (IAA/atherosclerotic lesion) | <.008 | |||||
| Cancer | IMUBIND | 215.6 ± 55.1 | 265.2 ± 124.3 | Mean ± SD | .014 | 53 |
| Breast cancer | IMUBIND | 115.35 (92.65-166.81) | 539.93 (400.94-710.40) | Median (IQR) | .0001 | 54 |
| IMUBIND | 110.9 ± 70.97 | Mean ± SD | 36 | |||
| Leukemia | IMUBIND | 172.2 ± 58.9 | Mean ± SD | 36 | ||
| Pancreatic adenocarcinoma | Quantikine | 52.4 (28.4-72.4) | 63.8 (32.7-112) (stage I-III) 82.8 (45.6-141) (metastatic) | Mean (range) | NS <.001 | 55 |
| Pancreatic adenocarcinoma | Quantikine | 39.1 (16.8-87.3) | 47.2 (0.0-224.8) (without CAT) | Median (range) | .009 | 33 |
| 56.0 (37.6-318.7) (with CAT) | .002 | |||||
| Multiple sclerosis | Quantikine | 110.85 ± 56.31 | 94.06 ± 55.83 (remitting) 45.03 ± 37.66 (relapsing) | Mean ± SD | <.001 | 56 |
| Quantikine | 45.01 ± 12.10 | Mean ± SD | 36 | |||
| Leukemia | Quantikine | 99.30 ± 78.66 | Mean ± SD | 36 |
| Disease . | Kit . | Healthy group TF antigen (pg/mL) . | Disease group TF antigen (pg/mL) . | Data type . | P value . | Reference . |
|---|---|---|---|---|---|---|
| Leukemia | IMUBIND | 117 ± 19.2 | 273 ± 90 | Mean ± SD | <.01 | 44 |
| Coronary artery disease | IMUBIND | 187.3 ± 108.7 | 303.6 ± 134.1 | Mean ± SD | <.05 | 45 |
| Peripheral artery disease | IMUBIND | 158 ± 60 | 275 ± 122 | Mean ± SD | <.0001 | 46 |
| Ischemic heart disease | IMUBIND | 142 (18-262) | 179.2 (51.2-380) (stable) 215 (56.8-834.3) (unstable) | Median (IQR) | <.0001 <.0001 | 47 |
| Coronary artery disease | IMUBIND | 76 (32-108) | 116 (92-150) (stable) | Median (IQR) | <.01 | 48 |
| 146 (104-188) (unstable) | <.001 | |||||
| Glomerulonephritis | IMUBIND | 144 ± 73.9 | 283 ± 145 | Mean ± SD | .009 | 49 |
| Non–small cell lung cancer | IMUBIND | 124.1 ± 14.79 | 334.9 ± 95.44 | Mean ± SD | .02 | 50 |
| Obstructive sleep apnea | IMUBIND | 42.83 ± 14.18 | 66.78 ± 41.59 | Mean ± SD | .005 | 51 |
| Aneurysm | IMUBIND | 62 ± 20 | 134 ± 54 (AAA) | Mean ± SD | <.001 | 52 |
| 91 ± 30 (IAA/atherosclerotic lesion) | <.008 | |||||
| Cancer | IMUBIND | 215.6 ± 55.1 | 265.2 ± 124.3 | Mean ± SD | .014 | 53 |
| Breast cancer | IMUBIND | 115.35 (92.65-166.81) | 539.93 (400.94-710.40) | Median (IQR) | .0001 | 54 |
| IMUBIND | 110.9 ± 70.97 | Mean ± SD | 36 | |||
| Leukemia | IMUBIND | 172.2 ± 58.9 | Mean ± SD | 36 | ||
| Pancreatic adenocarcinoma | Quantikine | 52.4 (28.4-72.4) | 63.8 (32.7-112) (stage I-III) 82.8 (45.6-141) (metastatic) | Mean (range) | NS <.001 | 55 |
| Pancreatic adenocarcinoma | Quantikine | 39.1 (16.8-87.3) | 47.2 (0.0-224.8) (without CAT) | Median (range) | .009 | 33 |
| 56.0 (37.6-318.7) (with CAT) | .002 | |||||
| Multiple sclerosis | Quantikine | 110.85 ± 56.31 | 94.06 ± 55.83 (remitting) 45.03 ± 37.66 (relapsing) | Mean ± SD | <.001 | 56 |
| Quantikine | 45.01 ± 12.10 | Mean ± SD | 36 | |||
| Leukemia | Quantikine | 99.30 ± 78.66 | Mean ± SD | 36 |
AAA, abdominal aortic aneurysm; CAT, cancer-associated thrombosis; IAA, inflammatory aortic aneurysm; IQR, interquartile range; NS, nonsignificant; SD, standard deviation.