Table 4.

Studies measuring TF in EV in plasma using the ZYMUPHEN MP-TF assay

Disease/treatmentSampleResultsReference
Deep infiltrating endometriosis PFP There was no difference between groups of patients with endometriosis with or without deep infiltration endometriosis 133  
Acute leukemia PFP 4 of 6 patients who had increased EV TF levels had a thrombotic event 134  
Acute ischemic stroke PFP Levels of EV TF activity were higher in patients with stroke than in healthy controls 135  
Cancer PPP Patients with cancer had higher levels of EV TF activity than healthy controls 122  
Immune thrombocytopenia PPP No difference in EV TF activity between patients with immune thrombocytopenia and controls 136  
Cancer and chemotherapy PFP Levels of EV TF activity did not change during chemotherapy but increased after the end of the treatment 137  
Sepsis PFP Levels of EV TF activity correlated with levels of interleukin-6 in plasma 138  
COVID-19 PFP Patients with COVID-19 had higher levels of EV TF activity than healthy controls 139  
Malaria PFP Patients with Plasmodium falciparum infection had increased levels of EV TF activity compared with controls 140  
Disease/treatmentSampleResultsReference
Deep infiltrating endometriosis PFP There was no difference between groups of patients with endometriosis with or without deep infiltration endometriosis 133  
Acute leukemia PFP 4 of 6 patients who had increased EV TF levels had a thrombotic event 134  
Acute ischemic stroke PFP Levels of EV TF activity were higher in patients with stroke than in healthy controls 135  
Cancer PPP Patients with cancer had higher levels of EV TF activity than healthy controls 122  
Immune thrombocytopenia PPP No difference in EV TF activity between patients with immune thrombocytopenia and controls 136  
Cancer and chemotherapy PFP Levels of EV TF activity did not change during chemotherapy but increased after the end of the treatment 137  
Sepsis PFP Levels of EV TF activity correlated with levels of interleukin-6 in plasma 138  
COVID-19 PFP Patients with COVID-19 had higher levels of EV TF activity than healthy controls 139  
Malaria PFP Patients with Plasmodium falciparum infection had increased levels of EV TF activity compared with controls 140  

PFP, platelet-free plasma; PPP, platelet-poor plasma.

Close Modal

or Create an Account

Close Modal
Close Modal