Laboratory data
| . | Patient 1 Age 36 y . | Patient 2 Age 34 y . | Patient 3 Age 4 y . |
|---|---|---|---|
| WBC (3.4 × 103-10.8 × 103) | 4.8 | 12.3 | 2.3 |
| HGB (11.1-15.9 g/dL) | 11.1 | 10.2 | 12.9 |
| HCT (34.0%-46.6%) | 34.1 | 33.3 | 38.0 |
| MCV (79-97 fL) | 97 | 72 | 86 |
| Platelets (150 × 103-379 × 103) | 442 | 503 | 181 |
| Lymphocytes count (0.7 × 103-3.1 × 103) | 3.6 | 10.2 | 0.9 |
| Monocytes count (0.1 × 103-0.9 × 103) | 0.7 | 1.2 | 0.1 |
| Eosinophils count (0.0 × 103-0.4 × 103) | 0.1 | 0.5 | 0.0 |
| Neutrophils count (1.4 × 103-7.0 × 103) | 0.4 | 0.3 | 0.5 |
| Basophils count (0.0 × 103-0.2 × 103) | 0.1 | 0.1 | 0.0 |
| IgG mg/dL (639-1349 mg /dL) | 633 | 601 | 630 |
| IgA mg/dL (70-312 mg/dL) | <5 | <5 | 143 |
| IgM mg/dL (56-352 mg/dL) | <5 | 208 | 173 |
| CD19 (56-698 mm3) | 11 | 17 | 59 |
| CD3 (790-2345 mm3) | 899 | 993 | 715 |
| CD4 (588-1202 mm3) | 423 | 741 | 615 |
| CD8 (156-856 mm3) | 434 | 222 | 77 |
| CD56 (79-527 mm3) | 148 | 48 | 114 |
| Memory B phenotypes: (%; mean ± SD∗ ) | |||
| CD27+ IgD, IgM− CD19+ (18.1 ± 5.1) | 0.00 | 1.90 | 0.58 |
| CD27+ CD19+ (41.4 ± 46.5) | 5.72 | 9.85 | 23.6 |
| CD27+ IgM+ IgD+ CD19+ (61.7 ± 10.42) | 97.9 | 95.5 | 90.3 |
| CD27+ CD24+ CD19+ (2.1 ± 0.8) | 78.0 | 45.2 | 34.2 |
| . | Patient 1 Age 36 y . | Patient 2 Age 34 y . | Patient 3 Age 4 y . |
|---|---|---|---|
| WBC (3.4 × 103-10.8 × 103) | 4.8 | 12.3 | 2.3 |
| HGB (11.1-15.9 g/dL) | 11.1 | 10.2 | 12.9 |
| HCT (34.0%-46.6%) | 34.1 | 33.3 | 38.0 |
| MCV (79-97 fL) | 97 | 72 | 86 |
| Platelets (150 × 103-379 × 103) | 442 | 503 | 181 |
| Lymphocytes count (0.7 × 103-3.1 × 103) | 3.6 | 10.2 | 0.9 |
| Monocytes count (0.1 × 103-0.9 × 103) | 0.7 | 1.2 | 0.1 |
| Eosinophils count (0.0 × 103-0.4 × 103) | 0.1 | 0.5 | 0.0 |
| Neutrophils count (1.4 × 103-7.0 × 103) | 0.4 | 0.3 | 0.5 |
| Basophils count (0.0 × 103-0.2 × 103) | 0.1 | 0.1 | 0.0 |
| IgG mg/dL (639-1349 mg /dL) | 633 | 601 | 630 |
| IgA mg/dL (70-312 mg/dL) | <5 | <5 | 143 |
| IgM mg/dL (56-352 mg/dL) | <5 | 208 | 173 |
| CD19 (56-698 mm3) | 11 | 17 | 59 |
| CD3 (790-2345 mm3) | 899 | 993 | 715 |
| CD4 (588-1202 mm3) | 423 | 741 | 615 |
| CD8 (156-856 mm3) | 434 | 222 | 77 |
| CD56 (79-527 mm3) | 148 | 48 | 114 |
| Memory B phenotypes: (%; mean ± SD∗ ) | |||
| CD27+ IgD, IgM− CD19+ (18.1 ± 5.1) | 0.00 | 1.90 | 0.58 |
| CD27+ CD19+ (41.4 ± 46.5) | 5.72 | 9.85 | 23.6 |
| CD27+ IgM+ IgD+ CD19+ (61.7 ± 10.42) | 97.9 | 95.5 | 90.3 |
| CD27+ CD24+ CD19+ (2.1 ± 0.8) | 78.0 | 45.2 | 34.2 |
HCT, hematocrit; HGB, hemoglobin; MCV, mean corpuscular volume; SD, standard deviation; WBC, whilte blood cell count
Normal range for adult controls.