Association of FVL and VTE outcomes within genetic ancestry groups and in a crosspopulation meta-analysis
| . | European . | Latine . | African . | Meta-analysis . |
|---|---|---|---|---|
| VTE | ||||
| OR (95% CI) | 3.31 (3.25-3.38) | 3.24 (2.98-3.52) | 2.83 (2.37-3.38) | 3.30 (3.24-3.37) |
| P value | <2.3e−308 | 5.5e−164 | 1.5e−30 | <2.3e−308 |
| PE | ||||
| OR (95% CI) | 2.72 (2.64-2.82) | 2.74 (2.39-3.15) | 2.40 (1.83-3.13) | 2.72 (2.64-2.81) |
| P value | <2.3e−308 | 1.1e−46 | 1.5e−10 | <2.3e−308 |
| Isolated DVT | ||||
| OR (95% CI) | 3.61 (3.52-3.70) | 3.49 (3.14-3.87) | 3.12 (2.48-3.93) | 3.59 (3.51-3.68) |
| P value | <2.3e−308 | 4.6e−122 | 2.5e−22 | <2.3e−308 |
| . | European . | Latine . | African . | Meta-analysis . |
|---|---|---|---|---|
| VTE | ||||
| OR (95% CI) | 3.31 (3.25-3.38) | 3.24 (2.98-3.52) | 2.83 (2.37-3.38) | 3.30 (3.24-3.37) |
| P value | <2.3e−308 | 5.5e−164 | 1.5e−30 | <2.3e−308 |
| PE | ||||
| OR (95% CI) | 2.72 (2.64-2.82) | 2.74 (2.39-3.15) | 2.40 (1.83-3.13) | 2.72 (2.64-2.81) |
| P value | <2.3e−308 | 1.1e−46 | 1.5e−10 | <2.3e−308 |
| Isolated DVT | ||||
| OR (95% CI) | 3.61 (3.52-3.70) | 3.49 (3.14-3.87) | 3.12 (2.48-3.93) | 3.59 (3.51-3.68) |
| P value | <2.3e−308 | 4.6e−122 | 2.5e−22 | <2.3e−308 |