Association between high DI and hematologic and nonhematologic toxicity
| Variable . | Hematologic toxicity . | Nonhematologic toxicity . | ||
|---|---|---|---|---|
| OR (95% CI) . | P value . | OR (95% CI) . | P value . | |
| Overall cohort | 2.1 (1.4-3.1) | <.001 | 0.9 (0.5-1.6) | .6 |
| MEMS subcohort | 2.8 (1.7-4.8) | <.001 | 1.1 (0.6-2.4) | .7 |
| MEMS subcohort, adherence ≥85% | 2.9 (1.6-5.1) | <.001 | 1.4 (0.6-3.1) | .4 |
| MEMS subcohort, adherence <85% | 2.1 (0.4-10.1) | .4 | 0.4 (0.0-5.6) | .5 |
| Variable . | Hematologic toxicity . | Nonhematologic toxicity . | ||
|---|---|---|---|---|
| OR (95% CI) . | P value . | OR (95% CI) . | P value . | |
| Overall cohort | 2.1 (1.4-3.1) | <.001 | 0.9 (0.5-1.6) | .6 |
| MEMS subcohort | 2.8 (1.7-4.8) | <.001 | 1.1 (0.6-2.4) | .7 |
| MEMS subcohort, adherence ≥85% | 2.9 (1.6-5.1) | <.001 | 1.4 (0.6-3.1) | .4 |
| MEMS subcohort, adherence <85% | 2.1 (0.4-10.1) | .4 | 0.4 (0.0-5.6) | .5 |
Each outcome adjusted for age at study entry, sex, and race/ethnicity. Outcomes examined in MEMS subcohort also adjusted for adherence.
OR, odds ratio.