Table 1. MRD and relapse made simple .... | American Society of Hematology

Table 1.

MRD and relapse made simple

	Relapse status
MRD status	Yes	No
Yes	Disease persists Test works!	Mutations not responsible for pre-malignant transformation and/or Mutation present in lineage not prone to leukemia and/or Active immune suppression and/or Other molecular reprogramming that prevents progression
No	Insufficient test sensitivity and/or Genetic marker instability and/or New clone/disease	No evidence of disease Test works!

	Relapse status
MRD status	Yes	No
Yes	Disease persists Test works!	Mutations not responsible for pre-malignant transformation and/or Mutation present in lineage not prone to leukemia and/or Active immune suppression and/or Other molecular reprogramming that prevents progression
No	Insufficient test sensitivity and/or Genetic marker instability and/or New clone/disease	No evidence of disease Test works!