Guideline recommendations for anticoagulation in VTE and AF
| Venous thromboembolism . | . | . | . |
|---|---|---|---|
| Guideline . | Indication for anticoagulation . | Duration . | Grade of evidence . |
| American Society of Hematology | |||
| Acute treatment for provoked and unprovoked VTE | 3-6 mo | Conditional, moderate certainty | |
| Long-term treatment for unprovoked VTE | Indefinitely | Conditional, moderate certainty | |
| Long-term treatment for VTE provoked by chronic risk factor | Indefinitely | Conditional, moderate certainty | |
| American College of Chest Physicians | |||
| Recurrent provoked VTE if history of unprovoked or provoked by chronic risk factor VTE | Indefinitely | Conditional, moderate certainty | |
| Acute treatment for provoked and unprovoked VTE | 3 mo | Strong, moderate certainty | |
| Long-term treatment for unprovoked or provoked by chronic risk factor VTE | Indefinitely | Strong, moderate certainty | |
| Superficial vein thrombosis of lower limb | 45 d | Weak, moderate certainty | |
| Cerebral venous sinus thrombosis | At least 3 mo | Strong, low certainty | |
| Acute isolated distal DVT and severe symptoms or risk of extension | At least 3 mo | Weak, low certainty | |
| Subsegmental PE with high risk of recurrence | At least 3 mo | Weak, low certainty | |
| Atrial fibrillation | |||
| Guideline | Anticoagulation recommendation | Grade of evidence | |
| American College of Cardiology/American Heart Association | |||
| Stroke prevention in AF if CHADS2VASC >/ = 2 in men or >/ = 3 in women | Indefinitely | Strong, high certainty | |
| Stroke prevention in AF if CHADS2VASC >/ = 1 in men or >/ = 2 in women | Indefinitely | Moderate, high certainty |
| Venous thromboembolism . | . | . | . |
|---|---|---|---|
| Guideline . | Indication for anticoagulation . | Duration . | Grade of evidence . |
| American Society of Hematology | |||
| Acute treatment for provoked and unprovoked VTE | 3-6 mo | Conditional, moderate certainty | |
| Long-term treatment for unprovoked VTE | Indefinitely | Conditional, moderate certainty | |
| Long-term treatment for VTE provoked by chronic risk factor | Indefinitely | Conditional, moderate certainty | |
| American College of Chest Physicians | |||
| Recurrent provoked VTE if history of unprovoked or provoked by chronic risk factor VTE | Indefinitely | Conditional, moderate certainty | |
| Acute treatment for provoked and unprovoked VTE | 3 mo | Strong, moderate certainty | |
| Long-term treatment for unprovoked or provoked by chronic risk factor VTE | Indefinitely | Strong, moderate certainty | |
| Superficial vein thrombosis of lower limb | 45 d | Weak, moderate certainty | |
| Cerebral venous sinus thrombosis | At least 3 mo | Strong, low certainty | |
| Acute isolated distal DVT and severe symptoms or risk of extension | At least 3 mo | Weak, low certainty | |
| Subsegmental PE with high risk of recurrence | At least 3 mo | Weak, low certainty | |
| Atrial fibrillation | |||
| Guideline | Anticoagulation recommendation | Grade of evidence | |
| American College of Cardiology/American Heart Association | |||
| Stroke prevention in AF if CHADS2VASC >/ = 2 in men or >/ = 3 in women | Indefinitely | Strong, high certainty | |
| Stroke prevention in AF if CHADS2VASC >/ = 1 in men or >/ = 2 in women | Indefinitely | Moderate, high certainty |