Table 3.

Univariable multinomial logistic regression for baseline clinical and PET metrics for HRDE subsets

VariablesFL24Early TFLLate TFLFL24 vs early TFL, P value
RRR95% CIFL24 vs Ref FL, P valueRRR95% CIEarly TFL vs Ref FL, P valueRRR95% CILate TFL vs Ref FL, P value
Female 0.93 0.49-1.76 .81 0.68 0.31-1.50 .34 0.64 0.16-2.61 .54 .53 
ECOG PS >2 2.07 0.74-5.80 .17 5.98 2.37-15.11 <.001 NA _ _ .092 
Stage III-IV 2.22 0.76-6.42 .14 1.97 0.58-6.71 .28 0.80 0.16-3.92 .78 .88 
Elevated LDH 2.86 1.50-5.46 .001 3.69 1.71-7.98 <.001 1.50 0.37-6.12 .57 .60 
Age >60 1.15 0.61-2.18 .66 1.49 0.69-3.26 .31 0.73 0.19-2.77 .64 .60 
>4 nodal sites 1.20 0.63-2.28 .59 0.73 0.34-1.56 .42 0.63 0.17-2.37 .49 .31 
Hb < 120 g/L 1.10 0.44-2.76 .83 2.16 0.87-5.36 .09 NA _ _ .28 
Grade 3A 0.39 0.05-3.06 .37 3.55 1.25-10.07 .02 NA _ _ .053 
BM involvement 1.24 0.58-2.63 .58 2.12 0.84-5.35 .11 0.94 0.16-5.73 .95 .36 
Elevated B2M 1.87 0.70-5.02 .21 7.06 2.34-21.32 <.001 0.80 0.09-7.35 .85 .065 
FLIPI low (0-1) 1.00 Reference .13 1.00 Reference .012 1.00 Reference .28 .83 
FLIPI Int (2) 1.38 0.50-3.83  1.15 0.27-4.96  0.17 0.02-1.57   
FLIPI high (3-5) 2.34 0.92-5.93  3.93 1.14-13.55  0.56 0.14-2.30   
VariablesFL24Early TFLLate TFLFL24 vs early TFL, P value
RRR95% CIFL24 vs Ref FL, P valueRRR95% CIEarly TFL vs Ref FL, P valueRRR95% CILate TFL vs Ref FL, P value
Female 0.93 0.49-1.76 .81 0.68 0.31-1.50 .34 0.64 0.16-2.61 .54 .53 
ECOG PS >2 2.07 0.74-5.80 .17 5.98 2.37-15.11 <.001 NA _ _ .092 
Stage III-IV 2.22 0.76-6.42 .14 1.97 0.58-6.71 .28 0.80 0.16-3.92 .78 .88 
Elevated LDH 2.86 1.50-5.46 .001 3.69 1.71-7.98 <.001 1.50 0.37-6.12 .57 .60 
Age >60 1.15 0.61-2.18 .66 1.49 0.69-3.26 .31 0.73 0.19-2.77 .64 .60 
>4 nodal sites 1.20 0.63-2.28 .59 0.73 0.34-1.56 .42 0.63 0.17-2.37 .49 .31 
Hb < 120 g/L 1.10 0.44-2.76 .83 2.16 0.87-5.36 .09 NA _ _ .28 
Grade 3A 0.39 0.05-3.06 .37 3.55 1.25-10.07 .02 NA _ _ .053 
BM involvement 1.24 0.58-2.63 .58 2.12 0.84-5.35 .11 0.94 0.16-5.73 .95 .36 
Elevated B2M 1.87 0.70-5.02 .21 7.06 2.34-21.32 <.001 0.80 0.09-7.35 .85 .065 
FLIPI low (0-1) 1.00 Reference .13 1.00 Reference .012 1.00 Reference .28 .83 
FLIPI Int (2) 1.38 0.50-3.83  1.15 0.27-4.96  0.17 0.02-1.57   
FLIPI high (3-5) 2.34 0.92-5.93  3.93 1.14-13.55  0.56 0.14-2.30   
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